LEEP治疗宫颈上皮内瘤变的临床分析  

作　　者：陆佳红[1] 何一波[1] 洪敏[1] 张薏[2] 徐文婷[2] 贾韩静 

机构地区：[1]浙江中医药大学第一临床医学院,310053 [2]浙江省中医院,310006

出　　处：《浙江临床医学》2017年第5期933-935,共3页Zhejiang Clinical Medical Journal

摘　　要：目的观察宫颈环形电切术（LEEP）治疗宫颈上皮内瘤变（CIN）的临床效果。方法2015年6月至2015年12日经LEEP治疗的宫颈液基细胞学涂片（TCT）、阴道镜活检后病理诊断为CINⅠ-Ⅲ级的患者50例为LEEP组，同期行冷刀锥切术（CKC）治疗的患者50例为对照组，观察两组患者的手术情况、术后并发症及治疗结果。结果LEEP组在手术时间短、术中出血量少、宫颈切口愈合时间短，各项指标明显优于CKC组，且差异有统计学意义（P〈0．05）。LEEP组术后并发症（术后出血、术后感染、宫颈粘连等）的发生率虽低于CKC组，但差异无统计学意义（P〉0．05）。LEEP组、CKC组治愈率分别为94％、78％，差异有统计学意义（P〈0．05）。结论宫颈环形电切术（LEEP）是目前治疗宫颈上皮内瘤变安全有效的方法，疗效确切，值得在临床上进一步推广及应用。Objective To investigate the clinical effect of loop electrical excision procedure （ LEEP ） in the treatment of cervical intraepithelial neoplasia （ CIN ） . Methods Retrospective analysis was carried out in 50 ICP cases who were diagnosed as CIN Ⅰ-Ⅲ by cervical liquid based cytology （ TCT ） and cervical biopsy by eolposcopy. 50 patients treated with cold knife cutting operation （ CKC ） were selected randomly as control group.The operation, postoperative complications and treatment results between two groups were observed. Result The operation time, the amount of bleeding during operation, the healing time of cervical incision of LEEP group was improved.These indicators of LEEP group were significantly better than the CKC group, and the difference was statistically significant （P〈0.05） . The incidence of postoperative complications （ bleeding, infection, cervical adhesion, etc. ） in group LEEP were lower than that in CKC group, but the difference was not statistically significant （ P〉0.05 ） .The cure rate of LEEP group and CKC group were 94% and 78% respectively, and the difference was significant （ P〈0.05 ） . Conclusion Loop electrical excision procedure （ LEEP ） is a safe and effective method for the treatment of cervical intraepithelial neoplasia. It is worth to be popularized and applied in clinic.

关 键 词：宫颈上皮内瘤变 宫颈环形电切术 临床效果 

分 类 号：R737.33[医药卫生—肿瘤]