热消融治疗在结直肠癌肝转移中的应用进展  

Perspective of thermal ablation in colorectal cancer with liver metastases

作　　者：周福波[1] 于晓玲[1] 梁萍[1] 程志刚[1] 韩志宇[1] 于杰[1] 刘方义[1] 孙亚[1] 

机构地区：[1]解放军总医院介入超声科,北京100853

出　　处：《解放军医学院学报》2017年第3期259-262,共4页Academic Journal of Chinese PLA Medical School

基　　金：国家自然科学基金项目(81471683)~~

摘　　要：约60%的结直肠癌患者疾病进展过程中伴发肝转移,手术切除为结直肠癌肝转移的标准疗法,但80%~90%的患者无法接受手术治疗。热消融技术是利用局部热能破坏肿瘤的治疗方法,近年来在多种无法切除的实体肿瘤中获得较好的临床疗效。在结直肠癌肝转移患者中,可使用的热消融技术主要为射频消融、微波消融、激光消融、不可逆电穿孔及冷冻消融。本文对热消融治疗后局部肿瘤进展、患者总体生存情况及并发症进行归纳,同时对热消融技术在消化道肿瘤肝转移中的应用前景进行展望。Approximately 60% of colorectal cancer patients will develop liver metastases during their disease course, and surgery is commonly believed as the standard treatment for colorectal cancer liver metastases （CRLM）. However, 80%- 90% CRLM patients are not candidates for surgical resection. Thermal ablation has been regarded as an alternative for treatment to unresectable solid tumors during the last decade. Radiofrequency ablation, microwave ablation, laser-induced thermal therapy, and cryoablation have been most commonly administered for patients with unresectable CRLM. In this review, we will summarize the efficacy of thermal ablation on CRLM, including local tumor progression, cumulative survival, and complications. Additionally, further evaluation of thermal ablation in patients with liver metastases from gastrointestinal tumors will be discussed.

关 键 词：热消融 结直肠癌 肝转移 

分 类 号：R735.3[医药卫生—肿瘤]