糖尿病膀胱病因与咖啡因对其治疗的研究进展  

Research progress about the cause of diabetic cystopathy and the treatment of it by caffeine

作　　者：张思聪 卫中庆 

机构地区：[1]南京医科大学第二附属医院(南京医科大学第二临床医学院)泌尿外科,南京医学硕士研究生210011

出　　处：《医学研究生学报》2017年第4期427-431,共5页Journal of Medical Postgraduates

基　　金：国家自然科学基金(81570687)

摘　　要：糖尿病膀胱是糖尿病引起的泌尿系统最常见的并发症之一,发病初期无明显临床表现,随着病情进展,各种复杂的下尿路症状逐渐出现,严重影响患者的生活质量和生命健康。但其发病机制尚不明确,肌源性和神经源性是其发病的主流学说。有研究提示长期饮用咖啡因可降低该病的发病率。文章将对此两种发病机制以及咖啡因对其治疗的相关研究进行探讨,以期为临床施治提供依据。Diabetic cystopathy is one of the most common complications caused by diabetes in urinary system. There were no obvious clinical manifestations in the early stage of the disease. With the progress of the disease, various complicated lower urinary tract symptoms appeared gradually. All these clinical manifestations cause grate trouble in the health and the quality of life of patients. How- ever, its pathogenesis is not clear, myogenic and neurogenic is the main theory of its pathogenesis. Some studies indicate that long-term consumption of caffeine can reduce the incidence of it, and this article will discuss the cause of this disease and the treatment of caffe- ine in order to guide clinical practice.

关 键 词：糖尿病膀胱 RYANODINE受体 降钙素基因相关肽 咖啡因 

分 类 号：R694[医药卫生—泌尿科学]