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作 者:Schirley Costalonga Jean Carlos Vencioneck Dutra Maria do Carmo Pimentel Batitucci
出 处:《Journal of Pharmacy and Pharmacology》2017年第5期261-269,共9页药剂与药理学(英文版)
摘 要:Invasive alien species are a global threat to biodiversity that affects protected areas around the world. The occupation of new environments by these plants is a problem to be solved and it is essential to investigate all the aspects that allow this successful to find solutions to this question, such as its mutagenic effects. Thus, this study aimed to evaluate the mutagenic effect of leaves extracts of Acacia mangium Willd, Artocarpus heterophyllus Lam and Eriobothrya japonica (Thunb.) Lindl through Allium cepa bioassay. For this, A. cepa seeds were submitted to continuous and discontinuous (acute and chronic) treatments in medium with water (negative control) or four concentration of each extract (1, 5, 10 and 50 mg/mL). The mitotic index was affected at all concentrations of three extracts tested in all treatments, continuous and discontinuous. Aneugenic effects were not related to any treatment tested. E. japonica extract induced clastogenic effects at 1, 5 and 10 mg/mL in continuous treatment, 5 and 10 mg/mL in acute discontinuous treatment and at 10 mg/mL in chronic discontinuous treatment. Clastogenic effect was also observed at 10 mg/mL ofA. heterophyllus extract in continuous and acute discontinuous treatments.
关 键 词:MUTAGENICITY biological contamination acacia mangium Willd artocarpus heterophyllus Lam eriobothrya japonica(Thunb.) Lindl.
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