MUTAGENICITY

作品数：97被引量：42H指数：4
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相关作者：王玉荣周安祥王子元林磊光王秀玲更多>>
相关机构：白银公司劳动卫生研究所哈尔滨医科大学中国科学院上海医科大学更多>>
相关期刊：《Journal of Cosmetics, Dermatological Sciences and Applications》《Science China Chemistry》《World Journal of Gastroenterology》《Journal of Pharmacy and Pharmacology》更多>>
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Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review
《Journal of Pharmaceutical Analysis》2024年第5期639-652,共14页Hemanth P.R.Vikram Tegginamath Pramod Kumar Gunjan Kumar Narasimha M.Beeraka Rajashree Deka Sheik Mohammed Suhail Sandeep Jat Namitha Bannimath Gayatiri Padmanabhan Ravandur S.Chandan Pramod Kumar Bannimath Gurupadayya 
The presence of N-nitroso compounds,particularly N-nitrosamines,in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.This systematic review investigates...
关键词：CARCINOGENICITY GENOTOXICITY MUTAGENICITY Molecular toxicity Nitrosamine impurities Nitrosamine drug substance-related IMPURITIES 
Anti-lipid-oxidation effects and edible safety evaluation of the oil extracted by a supercritical CO_(2) process from coix seed fermented by Monascus purpureus被引量：1
《Food Science and Human Wellness》2023年第4期1119-1127,共9页Haiying Zeng Anran Zhu Shengling He Mingjun Wu Muhammad Mazhar Anyan Wen Na Liu Likang Qin Song Miao 
supported by Natural Science Foundation of China(32260583);the Agriculture Committee of Guizhou Province[(2017)106&(2018)81];the Talent Introduction Program of Guizhou University[(2021)76].
The physicochemical properties and composition of coix seed oil produced by Monascus purpureus fermentation and supercritical CO_(2)extraction were determined.Anti-lipid-oxidation and edible safety were evaluated usin...
关键词：Coix seed oil Composition Edible safety MUTAGENICITY GENOTOXICITY 
Genotoxicity evaluation of two derived products from Allium extracts:s-propylmercaptocysteine and s-propyl mercaptoglutathione
《Food Bioscience》2023年第3期1603-1611,共9页Antonio Cascajosa-Lir Concepción Medrano-Padial Ana Isabel Prieto Alberto Baños José M.de la Torre Angeles Jos Ana M.Cameán 
Consejería de Economía y Conocimiento of Junta de Andalucía(AT17_5323_USE and P18-TP-2147);financial support and the CITIUS(University of Seville);Antonio Cascajosa Lira thanks the Spanish Ministerio de Universidades for the funding FPU grant(FPU2019-01247).
Propyl-propane-thiosulfonate(PTSO)is one of the main organosulfur compounds present in Allium essential oils with a widely documented biological activity.For this reason,it could be used as a food and feed additive in...
关键词：Cytotoxicity GENOTOXICITY MUTAGENICITY Organosulfur compounds ALLIUM Propyl-propane-thiosulfonate 
Disinfection byproducts in chlorinated or brominated swimming pools and spas: Role of brominated DBPs and association with mutagenicity
《Journal of Environmental Sciences》2022年第7期253-263,共11页Hannah K.Liberatore Eric J.Daiber Sridevi A.Ravuri Judith E.Schmid Susan D.Richardson David M.DeMarini 
supported by intramural funding through the Office of Research and Development of the U.S. Environmental Protection Agency。
Although the health benefits of swimming are well-documented, health effects such as asthma and bladder cancer are linked to disinfection by-products(DBPs) in pool water. DBPs are formed from the reaction of disinfect...
关键词：Swimming pools Hot tubs MUTAGENICITY Disinfection byproducts Spas 
In vitro toxicity of particulate matter emissions from residential pellet combustion
《Journal of Environmental Sciences》2022年第5期215-226,共12页Estela D.Vicente Daniela Figueiredo Catia Goncalves Isabel Lopes Helena Oliveira Nora Kovats Teresa Pinheiro Celia A.Alves 
We are also grateful for the support to CESAM(UIDB/50017/2020+UIDP/50017/2020);to FCT/MCTES through national funds,and co-funding by FEDER,within the PT2020 Partnership Agreement and Compete 2020;This study was financially supported by the project“Chemical and toxicological SOurce PROfiling of particulate matter in urban air(SOPRO)”,POCI-01-0145-FEDER-029574,funded by FEDER,through COMPETE2020-Programa Operacional Competitividade e Internacionalizacao(POCI);by national funds(OE),through FCT/MCTES and Programa Operacional Regional de Lisboa 2020(Project N.007317).FCT is also acknowledged for the research contract under Scientific Employment Stimulus to H.Oliveira(CEECIND/04050/2017);The Vibrio fischeri bioluminescent inhibition tests were supported by the BIONANO_GINOP-2.3.2-15-2016-00017 project.
Particulate matter emissions(PM10)from the combustion,in a residential stove,of two com-mercial brands of certified(ENplus A1)pellets,a non-certified brand and laboratory made pellets of acacia were tested for their a...
关键词：ECOTOXICITY Cytotoxicity MUTAGENICITY Fuel quality Pellet combustion PM10 emissions 
In vitro cytotoxic and toxicological activities of ethanolic extract of Kaempferia galanga Linn. and its active component,ethyl-p-methoxycinnamate, against cholangiocarcinoma被引量：1
《Journal of Integrative Medicine》2020年第4期326-333,共8页Porwornwisit Tritripmongkol Tullayakorn Plengsuriyakarn Mayuri Tarasuk Kesara Na-Bangchang 
funded by Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma of Thammasat University;Thammasat University Research fund under the TU Research Scholar(Contract No.03/2561)。
Objective:To evaluate the cytotoxic,apoptotic,mutagenic and immunomodulatory activities of Kaempferia galanga Linn.(KG)extract and ethyl-p-methoxycinnamate(EPMC)in vitro.Methods:The present study investigated the cyto...
关键词：Kaempferia galanga Linn. Cytotoxicity CHOLANGIOCARCINOMA MUTAGENICITY Apoptosis Immunomodulatory activity 
Mutagenic Potential of Medicinal Polyherbal Preparations
《Journal of Biosciences and Medicines》2019年第11期10-19,共10页Mohd Fuat Abd Razak 
Extracts of twelve medicinal polyherbal preparations in powder form sold at retail shops were tested for mutagenicity using Ames in vitro test. Five of the polyherbal preparations were found to be mutagenic (p ≤ 0.05...
关键词：AMES Test Mutagenic MUTAGENICITY POLYHERBAL SALMONELLA typhimuri-um TA100 
In-vivo Mutagenicity of Protein-modified Enterococcus faecalis
《Agricultural Biotechnology》2019年第3期92-94,共3页Lijun DING Shasha ZHAO 
Supported by Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(PPZY2015C230)
The mutagenicity of the protein-modified Enterococcus faecalis was evaluated by a mouse bone marrow micronucleus test and a mouse sperm abnormality test.The test substance was designed with three dose groups (1,2 and ...
关键词：Protein-modified E.faecalis MOUSE bone marrow MICRONUCLEUS TEST MOUSE sperm abnormality TEST 
Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process
《Biomedical and Environmental Sciences》2018年第8期632-636,共5页FANG Dao Kui ZHOU Guo Hong YU Shu Yuan FENG Jin Shu 
supported by grants from Science and Technology Planning Project of Shenzhen [No.200703079]
Purification of surface water is widely practiced with conventional water treatment processes like coagulation-flocculation, sedimentation, filtration,and disinfection. Some reports have specified that conventional wa...
关键词：Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process 
Mutagenic Effect of Three Invasive Species through Allium Cepa Bioassay被引量：1
《Journal of Pharmacy and Pharmacology》2017年第5期261-269,共9页Schirley Costalonga Jean Carlos Vencioneck Dutra Maria do Carmo Pimentel Batitucci 
Invasive alien species are a global threat to biodiversity that affects protected areas around the world. The occupation of new environments by these plants is a problem to be solved and it is essential to investigate...
关键词：MUTAGENICITY biological contamination acacia mangium Willd artocarpus heterophyllus Lam eriobothrya japonica（Thunb.） Lindl. 
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