GENOTOXICITY

作品数:145被引量:310H指数:8
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GC-MS Analysis,Antimicrobial Activity,and Genotoxicity of Pimpinella anisum Essential oil:In Vitro,ADMET and Molecular Docking Investigations
《Phyton-International Journal of Experimental Botany》2025年第3期809-824,共16页Ahmed Qasem 
Pimpinella anisum,commonly known as anise,is generally used in both folk medicine and the culinary world.In traditional medicine,it is valued for its digestive,respiratory,and antispasmodic properties.This study aims ...
关键词:ADMET molecular docking GENOTOXICITY ANTIMICROBIAL in vitro study anti-bacterial agents drug development 
Environmental genotoxicity assessment of nanoparticles using human airway epithelial model
《Emerging Contaminants》2024年第4期308-316,共9页Sirirak Hemmaphan Kotchapawn Somprasong Narisa K.Bordeerat 
supported by the Thailand Science Research and Innovation Fundamental Fund(TUFF 46/2565);by Thammasat University Research Fund(TUFT-FF 38/2565).
Because of the growing use of nanoparticles(NPs)in manufacturing consumer goods,it is essential to identify new in vitro approaches to assess their toxicity and improve risk assessment.Humans are exposed to NPs from c...
关键词:GENOTOXICITY NANOPARTICLES Human bronchial/tracheal epithelial cell 3D spheroid 
Spatio-temporal characteristics of genotoxicity in the Yangtze River under the background of COVID-19 pandemic
《Frontiers of Environmental Science & Engineering》2024年第11期121-132,共12页Xinge Wang Na Li Yingnan Han Xiao Li Weixiao Qi Jian Li Kaifeng Rao Zijian Wang Yanjie Wei Mei Ma 
supported by the National Key Research and Development Program(No.2021YFC3200803);the Scientific Research Project of China Three Gorges Corporation(No.201903139);the National Key R&D Program of China(No.2021YFC3200102);the National Natural Science Foundation of China(No.42007227);the National Natural Science Foundation of China(No.52030003);the Natural Science Foundation of Tianjin(No.22YFYSHZ00060).
The global spread of viruses can lead to the release of large amounts of disinfectants or antiviral drugs into the water environment.The resulting disinfection byproducts(DBPs)and residual antiviral drugs,acting as ge...
关键词:Yangtze River COVID-19 GENOTOXICITY Spatio-temporal characteristics 
Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review
《Journal of Pharmaceutical Analysis》2024年第5期639-652,共14页Hemanth P.R.Vikram Tegginamath Pramod Kumar Gunjan Kumar Narasimha M.Beeraka Rajashree Deka Sheik Mohammed Suhail Sandeep Jat Namitha Bannimath Gayatiri Padmanabhan Ravandur S.Chandan Pramod Kumar Bannimath Gurupadayya 
The presence of N-nitroso compounds,particularly N-nitrosamines,in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.This systematic review investigates...
关键词:CARCINOGENICITY GENOTOXICITY MUTAGENICITY Molecular toxicity Nitrosamine impurities Nitrosamine drug substance-related IMPURITIES 
Biotoxicity dynamic change and key toxic organics identification of coal chemical wastewater along a novel full-scale treatment process被引量:2
《Journal of Environmental Sciences》2024年第4期277-287,共11页Weiwei Ma Xiaoqi Zhang Hongjun Han Xueqing Shi Qiaoping Kong Tong Yu Fei Zhao 
supported by the Natural Science Foundation of Shandong Province,China(No.ZR2021QE227);the Natural Science Foundation of Shandong Province,China(No.ZR2021QE272);the Open Project of State Key Laboratory of Urban Water Resource and Environment,Harbin Institute of Technology(No.ES202120);the Taishan Scholars Program of Shandong Province,China(No.tsqn201812091)。
It is particularly important to comprehensively assess the biotoxicity variation of industrial wastewater along the treatment process for ensuring the water environment security.However,intensive studies on the biotox...
关键词:Acute biotoxicity GENOTOXICITY Oxidative damage Toxic organics Coal chemical wastewater Novel full-scale treatment process 
A therapeutic potentiality and toxicity concern of nutrient plant Annona squamosa Linn.
《Traditional Medicine Research》2024年第3期52-65,共14页Manisha Chandrakar Khomendra Kumar Sarwa Vijendra Kumar Suryawanshi Kumari Pramila 
Annona squamosa Linn.fruit is famous for its nutritional value with a long history of medicinal benefits due to the presence of many phytochemicals,including alkaloids,diterpenes,essential oil,phytopeptides,etc.Severa...
关键词:Annona squamosa CYTOTOXICITY cancer abortifacient GENOTOXICITY isosquamocin annonacin NEUROTOXICITY ocular toxicity 
Enhancement of the Antigenotoxic and Antioxidant Actions of Eugenol from Spice Clove and the Stabilizer Gum Arabic on Colorectal Carcinogenesis
《Food and Nutrition Sciences》2024年第1期71-100,共30页Nayanna de Oliveira Ramos Melo Lucas Gabriel da Costa Marques Humberto Maia Costa Neto Matheus De Sousa Silva Francisco Vagnaldo Fechine Jamacaru Bruno Coêlho Cavalcanti Antônio Adailson De Sousa Silva Conceição Aparecida Dornelas 
Spices are defined as any aromatic condiment of plant origin used to alter the flavor and aroma of foods. Besides flavor and aroma, many spices have antioxidant activity, mainly related to the presence in cloves of ph...
关键词:EUGENOL Gum Arabic CARCINOGENESIS Oxidative Stress GENOTOXICITY 
Anti-lipid-oxidation effects and edible safety evaluation of the oil extracted by a supercritical CO_(2) process from coix seed fermented by Monascus purpureus被引量:1
《Food Science and Human Wellness》2023年第4期1119-1127,共9页Haiying Zeng Anran Zhu Shengling He Mingjun Wu Muhammad Mazhar Anyan Wen Na Liu Likang Qin Song Miao 
supported by Natural Science Foundation of China(32260583);the Agriculture Committee of Guizhou Province[(2017)106&(2018)81];the Talent Introduction Program of Guizhou University[(2021)76].
The physicochemical properties and composition of coix seed oil produced by Monascus purpureus fermentation and supercritical CO_(2)extraction were determined.Anti-lipid-oxidation and edible safety were evaluated usin...
关键词:Coix seed oil Composition Edible safety MUTAGENICITY GENOTOXICITY 
Research progress on the effects of phthalates on reproductive health of childbearing population and their offspring
《Journal of Hainan Medical University》2023年第16期61-68,共8页LIN Cai-yun YIN Fei-fei WANG Hui-zi YANG Hua 
Hainan Province Clinical Medical Center (No.QWYH202175).
The total fertility rate of women in childbearing age showed a downward trend in China.In addition to the age and genetic factors,environmental endocrine disruption can also impair fertility.The impact of increasing n...
关键词:PAES People of reproductive age Reproduction toxicity GENOTOXICITY 
Comprehensive Assessment of the Safety of Eucommia ulmoides Leaf Extract for Consumption as a Traditional Chinese Health Food被引量:2
《Journal of Renewable Materials》2023年第7期3091-3114,共24页Huiling Fu Mijun Peng Qiuwen Tang Haojun Liang Yanli Liang Jiali Fang Xuesong Wang 
This study was supported by the National Natural Science Foundation of China(Grant No.42107020);the Scientific Research Start Funds,Hunan Institute of Technology(No.HQ20014)。
To ensure the export quality of Eucommia ulmoides leaf extract(ELE)and facilitate E.ulmoides leaf inclusion in the directory of traditional Chinese health foods,an overall safety assessment of ELE was performed,includ...
关键词:Eucommia ulmoides leaf extract GENOTOXICITY long-term toxicity growth performance bioactivity 
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