经导管封堵术治疗卵圆孔未闭合并隐匿性卒中或短暂性缺血发作的近中期疗效观察  

Short and Mid-term Efficacy of Device Closure of Patent Foramen Ovale for Treating the Patients With Patent Foramen Ovale Combining Cryptogenic Stroke and Transient Ischemic Attack

作　　者：黄浩佳 胡海波[1] 徐仲英[1] 张戈军[1] 潘湘斌[2] 郑宏[1] 金敬琳[1] 吕建华[1] 李世国[1] 闫朝武[1] 徐亮[1] 万俊义[1] 刘琼[1] 蒋世良[1] 

机构地区：[1]北京协和医学院中国医学科学院国家心血管病中心阜外医院放射科,北京市100037 [2]北京协和医学院中国医学科学院国家心血管病中心阜外医院心外科,北京市100037

出　　处：《中国循环杂志》2017年第4期377-379,共3页Chinese Circulation Journal

摘　　要：目的:探讨经导管封堵术治疗卵圆孔未闭(PFO)合并隐匿性卒中或短暂性缺血发作的近中期疗效。方法:随访2009-05至2015-12期间在阜外医院成功实施经导管PFO封堵术的PFO合并隐匿性卒中、短暂性缺血发作56例,并于术后24h、1个月、3个月、6个月复查经胸超声心动图、心电图、X线胸片,随后每隔6个月行电话随访。结果:56例患者中合并隐匿性卒中54例,合并短暂性缺血发作2例,53例(94.6%)使用北京华医圣杰公司PFO封堵器,术后应用阿司匹林6个月,平均随访(34.67±23.24)个月,所有患者术后均无卒中、短暂性缺血发作病史,术后均未见残余分流。结论:经导管PFO封堵术治疗PFO合并隐匿性卒中或短暂性脑缺血发作近中期疗效满意,仍需要进一步长期大规模随访。ctive： To explore the short and mid-term efficacy of device closure of patent foramen ovale （PFO） for treating the patients with PFO combining cryptogenic stroke （CS） and transient ischemic attack （TIA）. Methods： A total of 56 PFO patients with CS and TIA receiving device closure in our hospital from 2009-05 to 2015-12 were retrospectively studied. Transthoracic echocardiography （TTE）, electrocardiogram （ECG）, chest X-ray were examined at 24h, 1 month, 3 and 6 months after theoperation; telephone visit was conducted every 6 months thereafter. Results： There were 54/56 PFO patients combining CS and 2 combining TIA; 53 （94.6%）patients received PFO occluder from Starway medical technology. Aspirin was used for 6 months after the operation. The patients were followed-up for the average of （34.67±23.24） months. No body suffered from post-operative stroke and TIA; no residual shunt was observed. Conclusion： The short and mid-term efficacy of device closure has been satisfactory for treating the patients with PFO combining CS and TIA; its overall clinical value should be further investigated in large population and long-term study.

关 键 词：心脏缺损 先天性 卒中 间隔封堵器 

分 类 号：R743.31[医药卫生—神经病学与精神病学]