外泌体与口腔疾病关系的研究进展  

Research progress on exosomes and oral diseases

作　　者：吴佳梦 王效英[1] 

机构地区：[1]山东大学口腔医院牙体牙髓病科山东省口腔组织再生重点实验室,济南250012

出　　处：《国际口腔医学杂志》2017年第3期336-339,共4页International Journal of Stomatology

摘　　要：外泌体是由各种类型的细胞分泌的多形性囊泡样小体,其中含有蛋白质和RNA等多种成分,具有抗肿瘤免疫、促血管新生等生理功能,并且与口腔疾病密切相关。外泌体可作为口腔癌、口腔黏膜病、唾液腺疾病等口腔疾病诊断的生物标志物,还有作为口腔癌候选抗癌疫苗的可能。本文主要就外泌体及其与口腔疾病的关系作一综述。Exosomes secreted by various types of cells are small vesicular bodies that contain many types of proteins and RNAs. They have multiple functions, such as anti-tumor immunity and angiogenesis. Their possible use as oral disease biomarkers and vaccine candidates was also discussed. This review presents recent advances in exosomes and the relationship with oral diseases.

关 键 词：外泌体 口腔疾病 生物标志物 

分 类 号：R78[医药卫生—口腔医学]