精神分裂症患者应用行为治疗组合临床疗效分析  

Analysis of Clinical Efficacy of Behavioral Therapy in Patients with Schizophrenia

作　　者：高海江[1] 陈妍华[1] 王兴生[1] 高海英[1] 强瑞香 张淑艳[1] 孟雪松[1] 赵艳名 

机构地区：[1]河北省秦皇岛市九龙山医院,河北秦皇岛066000

出　　处：《河北医学》2017年第4期610-613,共4页Hebei Medicine

基　　金：河北省秦皇岛市科技局2012年科技支撑计划;(编号:2012023A030)

摘　　要：目的:探讨行为治疗组合在精神分裂症的临床应用效果。方法:选取秦皇岛市九龙山医院2012年4月至2015年4月三年期间住院的重性精神疾病管理治疗项目之精神分裂症患者369例为研究对象,动态随机化分为两组,184例给予行为治疗组合加利培酮治疗、185例单独予以利培酮治疗8周。采用阳性与阴性症状量表(PANSS)评定疗效,不良反应量表(TESS)、锥体外系副反应量表(RSESE)评定不良反应。结果:研究组临床疗效优于对照组,治疗总有效率两组比较差异有统计学意义(P<0.05)。两组在治疗各期的组内及组间PANSS评分差异具有统计学意义(P<0.05)。研究组的不良反应低于对照组,差异具有统计学意义(P<0.05)。结论:行为治疗组合在精神分裂症的临床应用效果明显,不良反应低,值得推广。Objective：To explore the clinical application of behavior therapy combination in schizophrenia.Methods： 369 cases of schizophrenia patients admitted in Jiulongshan hospital of qinhuangdao city from April 2012 to April 2015 were selected as the research objects.All patients were randomly divided into two groups, the treatment group was treated with risperidone combined with risperidone, and the treatment group was treated with risperidone for 8 weeks for the first time in 184 cases.The positive and negative symptom scale （PANSS） was used to evaluate the therapeutic effect.Adverse reaction scale （TESS） and extrapyramidal side effects scale （RSESE） were used to evaluate adverse reactions.Results： The clinical efficacy of the study group was better than that of the control group.The total effective rate of the two groups was statistically significant （P〈0.05）.There were significant differences in the PANSS scores between the two groups during the treatment period （P〈0.05）.The adverse reactions in the study group were lower than those in the control group （P〈0.05）.Conclusion： The clinical effect of the combination of behavioral therapy in schizophrenia is obvious, and the adverse reaction is low.

关 键 词：精神分裂症 行为治疗组合 临床疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]