中药漱口水联合含氟涂料防治儿童牙龋病的效果及对口腔Hp感染的影响  

Effect of TCM Mouthrinse Combined with Fluoride Varnish in Prevention and Treatment of Children with Caries and Its Influence on Oral Hp Infection

作　　者：张玉杰[1] 赵晓军[1] 赵丽[1] 张雪飞[1] 张江畔 于静[1] 胡永权[1] 

机构地区：[1]石家庄市第二医院口腔科,石家庄050051

出　　处：《解放军医药杂志》2017年第4期109-112,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的观察中药漱口水联合含氟涂料防治儿童牙龋病的效果及对口腔Hp感染的影响。结果选取2013年2月—2014年8月石家庄市中心城辖区6所幼儿园共420名儿童,按防治方法分为对照组和观察组,每组210例,对照组接受局部含氟涂料预防治疗,观察组在对照组基础上加用中药漱口水,涂氟后第2天开始口含中药漱口水。比较2组儿童患龋率、乳牙龋面均(DMFS)、显著性龋均指数(SIC)及防治前后口腔Hp变化情况。结果防治前2组患龋率、DMFS、SIC和口腔Hp感染率比较差异无统计学意义(P>0.05)。防治后1年和2年,2组患龋率、DMFS、SIC和口腔Hp感染率较防治前上升,但观察组低于对照组,差异有统计学意义(P<0.05);2组防治后SIC比较差异无统计学意义(P>0.05)。2组不良反应发生率比较差异无统计学意义(P>0.05)。结论中药漱口水联合含氟涂料防治儿童牙龋病的效果及对口腔Hp感染的改善要优于单独使用含氟涂料,含氟涂料最佳防龋效果还需进一步研究。Objective To observe effect of traditional Chinese medicine （TCM） mouthrinse combined with fluoride varnish in prevention and treatment of children with caries and its influence on oral Hp infection. Methods A total of 420 children from 6 kindergartens in the urban area of the city center between February 2013 and August 2014 were divided into control group and observation group （n = 210 for each group） according to prevention and treatment methods. Control group was treated with local preventive therapy with fluoride varnish, while observation group was treated with TCM mouthrinse on the 2^nd day after application of fluoride varnish on the basis of treatment in control group. Caries prev-alence rate, decayed, missing or filling surfaces （DMFS） , significant caries index （SIC） and changes of oral Hp before and after treatment were compared between the two groups. Results Before treatment, there were no significant differences in caries prevalence rate, DMFS, SIC and incidence rate of oral Hp infection between the two grouPs （P 〉 0.05） ; Caries prevalence rate, DMFS, SIC and incidence rate of oral Hp infection 1 year and 2 years after prevention and treat- ment were significantly increased compared with those before treatment in the two groups, and the values in observation group were significantly lower than those in control group （ P 〈 0.05 ）. There was no significant difference in SIC after prevention and treatment between the two groups （ P 〉 0.05 ）. There was no significant difference in incidence rate of adverse reactions between the two groups （P〉0. 05）. Conclusion TCM mouthrinse combined with fluoride varnish in prevention and treatment caries and improvement of oral Hp infection has better effect compared with that by fluoride varnish alone.

关 键 词：龋齿 漱口药 氟化物 外用 幽门螺杆菌 

分 类 号：R781.1[医药卫生—口腔医学]