男性肿瘤患者生育力保存的现状与展望  

Current situation and prospect of fertility preservation in male cancer patients

作　　者：刘茜[1] 邢柳 王彩奕 欧紫薇 陈琪[1] 张舒萍[1] 范立青[2,3] 

机构地区：[1]中南大学湘雅医学院,长沙410013 [2]中信湘雅生殖与遗传专科医院,长沙410078 [3]中南大学基础医学院生殖与干细胞工程研究所,长沙410078

出　　处：《中国医师杂志》2017年第4期481-486,共6页Journal of Chinese Physician

摘　　要：随着肿瘤学科的高速发展，诊疗技术的不断进步，尽管肿瘤发病率在逐年上升，但是肿瘤患者病死率在下降，幸存的男性肿瘤患者越来越重视自身预后生活质量的提高，而能否成功生育自己的后代成为预后良好的肿瘤患者最关心的问题。然而，目前男性肿瘤患者、家属以及社会各界，甚至部分医疗工作者对男性肿瘤患者生育力保存的重视程度不足，没有充分考虑肿瘤患者的远期生育意愿，导致抗肿瘤治疗前未及时进行生育力保存，进而造成生育力下降甚至不可逆的损伤。男性肿瘤患者及时进行生育咨询，并了解治疗方案对生育力损伤的风险以及选择合适的生育力保存技术是改善我国男性肿瘤患者预后生活质量的重要途径。本文从肿瘤及治疗对男性生育力影响、肿瘤患者对生育力保存的主观需求和顾虑、男性肿瘤患者生育力保存的主要方法和国内外生育力保存现状方面进行了系统阐述。With the rapid development of tumor subjects and the advance of medical technology, tumor mortality is declining in spite of the increase in tumor incidence. The male survivors pay more and more attention to their prognosis to improve the quality of their life. In the meantime, whether they could produce their own offspring become the main concern of tumor patients with good prognosis. However, until now, male tumor patients, their relatives, different social sectors and even some of our health work- ers, havent noticed the importance of fertility preservation and long-term fertility desires of male patients with tumor which will lead to declined or even irreversible sterility induced by the lack of fertility preser- vation before anti-tumor therapy. It＇s an important way to do fertility counseling, learn the risk of their treatment plans and choose the appropriate technique of fertility preservation which will improve prognosis quality of life of male tumor patients. This artic]e will review the effects of tumor and the treatment on male fertility, their subjective needs and concerns, main methods for fertility preservation and the domes- tic and foreign research present situation.

关 键 词：肿瘤 生育力 述评 

分 类 号：R730.5[医药卫生—肿瘤]