急性基底动脉闭塞所致脑梗死的起病特征与病变部位的相关性  

Relationship between lesion location and onset symptoms of cerebral infarction caused by acute basilar arterial occlusion

作　　者：王明[1] 殷勤[1] 李敏[1] 高洁[1] 林梦洁 赵娜娜[1] 马敏敏[1] 

机构地区：[1]南方医科大学金陵医院(南京军区南京总医院)神经内科,南京医学硕士研究生210002 [2]云南省德宏州人民医院神经内科,德宏678400

出　　处：《医学研究生学报》2017年第5期508-511,共4页Journal of Medical Postgraduates

基　　金：国家自然科学基金(81671170;81601036;81501027)

摘　　要：目的基底动脉闭塞所致脑梗死的临床表现错综复杂。文中旨在探讨其起病特征与病变部位的相关性。方法纳入南京市卒中注册系统中2007年1月至2016年7月在南京总医院住院治疗的53例首发急性基底动脉闭塞所致后循环梗死患者的临床资料,根据起病形式将患者分为急进型组及缓慢进展组,结合脑血管造影结果进行回顾性分析。结果急进型组血管闭塞部位多位于基底动脉中段及上段,缓慢进展组则多为基底动脉下段。组间比较差异有统计学意义(P<0.05)。Logistic回归分析结果显示,与基底动脉上段闭塞患者相比,下段闭塞患者的起病方式更倾向于缓慢进展型(OR=14.77,95%CI:1.57~139.00,P=0.019)。结论急性基底动脉闭塞所致脑梗死的起病特征与病变部位具有相关性。早期诊断、及时治疗有助于改善患者的临床预后。Objective The clinical manifestations of cerebral infarction caused by acute basilar arterial occlusion are complex. The purpose of this study is to explore the relationship between lesion location and onset symptoms of cerebral infarction caused by acute basilar arterial occlusion. Methods Fifty three patients diagnosed with cerebral infarction caused by acute artery occlusion were collected from Nanjing Stroke Registry. They were hospitalized in Jinling Hospital from January 2007 to July 2016 and were divided into sudden onset group and progressive onset group. Their clinical and digital subtraction angiography data were analyzed retrospectively. Results Middle and distal segment of the basilar artery occlusions were usually found in sudden onset group. Patients in progressive onset group were more likely to present with proximal segment of the basilar artery occlusions. Significant statistical difference was found between two groups（ P〈0.05）. Logistic regression analysis showed that the symptoms of patients with proximal segment basilar artery occlusion tended to be progressive onset,compared with patients affected by distal segment occlusion（ OR = 14. 77,95% CI：1.57-139.00,P = 0.019）. Conclusion There was significant relationship between lesion location and onset symptoms of cerebral infarction caused by acute basilar arterial occlusion. Early diagnosis and timely treatment may improve clinical prognosis in patients.

关 键 词：基底动脉闭塞 脑梗死 起病特征 病变部位 

分 类 号：R743[医药卫生—神经病学与精神病学]