血管新生介导甲状旁腺素对靶器官代谢调控作用的研究进展  

Process of neovascularization in mediating regulation of parathyroid hormone on metabolism of target organs

作　　者：姜鑫[1] 程群[1] 

机构地区：[1]复旦大学附属华东医院骨质疏松科,老年医学研究所骨代谢研究室,上海200040

出　　处：《中华内分泌代谢杂志》2017年第4期351-354,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金资助项目（81471089）;上海卫生系统重要疾病联合攻关项目（2013ZYJB0801）

摘　　要：血管新生是组织损伤修复、肿瘤生长及激素作用等过程必不可少的环节，甲状旁腺素（PTH）作为调节机体钙、磷与骨代谢稳态的基础激素，近年关于血管新生介导PTH发挥代谢调控作用的研究逐渐兴起，本文就PTH对靶器官尤其对骨组织作用时相应的血管新生变化进行综述。Neovascularization plays an essential role in the process of renovation in tissue damage, tumor growth, and hormones action. Parathyroid hormone （PTH） is one of the basic hormones that regulate the serum calcium, phosphorus, and bone metabolism. In recent years, studies involving the neovascularization-mediated effects of PTH on metabolism are becoming more and more popular and wider. Based on recent researches, the purpose of this paper is to summarize the changes of angiogenesis while PTH interacts with its target organs, especially interacts with osseous tissue.

关 键 词：甲状旁腺素 血管新生 骨代谢 甲状旁腺激素相关肽 

分 类 号：R363[医药卫生—病理学]