声触诊组织定量在胰腺局灶性病变鉴别诊断中的初步应用  

Initial Experience in the Application of Virtual Touch Tissue Quantification in the Differential Diagnosis of Focal Pancreatic Lesions

作　　者：韩洁[1] 吕珂[1] 姜玉新[1] 戴晴[1] 李建初[1] 何蒙娜[1] 高嫔[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院超声医学科,北京100730

出　　处：《中国医学科学院学报》2017年第2期266-271,共6页Acta Academiae Medicinae Sinicae

基　　金：公益性行业基金(201402001)~~

摘　　要：目的探讨声触诊组织定量(VTQ)鉴别胰腺局灶性病变应用价值。方法对51例胰腺占位患者行VTQ检查,分别获取病灶剪切波速(LSWV)、相邻胰腺实质剪切波速(PSWV)及剪切波速差值(DSWV)(DSWV=LSWVPSWV),对照病理结果或临床诊断,评估LSWV、PSWV和DSWV在胰腺局灶性病变的鉴别诊断价值。结果恶性组的LSWV和PSWV分别为(2.39±1.25)m/s(0.60~4.39 m/s)和(1.59±0.63)m/s(0.76~3.22 m/s);潜在恶性组的LSWV和PSWV分别为(1.92±1.07)m/s(0.79~4.00 m/s)和(1.43±0.41)m/s(0.80~2.23 m/s);良性组的LSWV和PSWV分别为(2.40±1.10)m/s(0.89~3.42 m/s)和(1.48±0.44)m/s(1.03~2.11 m/s);良、恶性组内LSWV和PSWV差异有统计学意义(P=0.029,P=0.005),潜在恶性组的LSWV和PSWV差异无统计学意义(P=0.087)。LSWV、PSWV和DSWV在3组间差异无统计学意义(P=0.401,P=0.638,P=0.625)。LSWV与病灶大小不相关(r=0.253,P>0.05);LSWV与感兴趣区深度呈负相关(r=-0.413,P<0.05)。结论利用VTQ鉴别诊断胰腺局灶性病变的价值有待进一步的研究。Objective To explore the potential value of the virtual touch tissue quantification（ VTQ）in the differential diagnosis of focal pancreatic lesions. Methods Totally 51 patients with focal pancreatic lesions underwent the quantitative analysis by VTQ. Based on the pathologic or clinical diagnosis,the VTQ values including lesional shear wave velocity（ LSWV）,parenchymal shear wave velocity（ PSWV）,and difference shear wave velocity（ DSWV）（ DSWV = LSWV-PSWV） were compared between the lesions and background parenchyma. Results The mean LSWV and PSWV were（ 2. 39 ± 1. 25） m/s（ 0. 60-4. 39 m/s） and（ 1. 59 ± 0. 63）m/s（ 0. 76-3. 22 m/s） in malignant group,（ 1. 92 ± 1. 07） m/s（ 0. 79-4. 00 m/s） and（ 1. 43 ± 0. 41） m/s（ 0. 80-2. 23 m/s） in potentially malignant group,and（ 2. 40 ± 1. 10） m/s（ 0. 89-3. 42 m/s） and（ 1. 48 ±0. 44） m/s（ 1. 03-2. 11 m/s） in benign group. There were statistically significant difference between LSWV andPSWV in bengin and malignant group（ P = 0. 029,P = 0. 005）,while no statistical significance in potential malignant group（ P = 0. 087）. However,LSWV,PSWV,and DSWV showed no significant difference among these three groups（ P = 0. 401,P = 0. 638,P = 0. 625,respectively）. LSWV was not significantly associated with the tumor size（ r = 0. 253,P〉0. 05） but had negative correlation with the depth of region of interest（ r =-0. 413,P〈0. 05）. Conclusion VTQ may be valuable in the differential diagnosis of focal pancreatic lesions,although further research is still required.

关 键 词：声触诊组织定量 剪切波速 胰腺占位 诊断 

分 类 号：R576[医药卫生—消化系统] R445.1[医药卫生—内科学]