汉族与维吾尔族慢性根尖周炎患者根管治疗后疼痛差异及口服布洛芬后镇痛效果比较  

Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after singlevisit root canal therapy between Uyghur and Han patients with chronic apical periodontitis

作　　者：闫磊[1,2] 王新迎[1] 万娜[1] 尹艳娇 吴佩玲[1] 

机构地区：[1]新疆医科大学第二附属医院口腔科,新疆乌鲁木齐830063 [2]新疆军区总医院口腔科,新疆乌鲁木齐830000

出　　处：《上海口腔医学》2017年第2期217-221,共5页Shanghai Journal of Stomatology

摘　　要：目的 :比较汉族、维吾尔族慢性根尖周炎患者根管治疗术后疼痛发生率,比较布洛芬对汉族、维吾尔族慢性根尖周炎患者一次性根管治疗后疼痛的镇痛效果,优化术后用药方案。方法:选取切牙、尖牙、前磨牙单根管慢性根尖周炎的汉族、维吾尔族患者各250例,均给予一次性根管充填治疗。术后按照随机双盲原则,分别将维吾尔族患者分为实验组(维)、对照组(维),将汉族患者分为实验组(汉)和对照组(汉)。其中实验组患者参照说明书,服用布洛芬缓释胶囊,对照组患者则服用安慰剂(淀粉胶囊),医生与患者在整个实验过程中对分组和服药情况均保持不知情。利用VAS痛觉量表记录患者术后6、12、24、48、72 h和1周的疼痛程度,采用SPSS11.0软件包对数据进行χ2检验。结果:实验期间,各组患者根管治疗后疼痛的发生率从大至小依次为对照组(维)>对照组(汉)>实验组(维)>实验组(汉),各组两两之间均有显著差异。从时间分布上来看,根管治疗后疼痛多发生于24~48 h之间,疼痛的最大值也多集中在这一时间段。不论是根管治疗术后疼痛的发生率还是剧烈程度,实验组(汉)与对照组(汉)之间的差异,均比实验组(维)和对照组(维)之间的差异更为显著。结论:单根管慢性根尖周炎一次性根管治疗后,维吾尔族患者疼痛发生率高于汉族患者;服用布洛芬对于维吾尔族和汉族患者都能有效预防、缓解根管治疗中疼痛,但是布洛芬对于维吾尔族患者的镇痛效果不如对汉族患者的镇痛效果明显。PURPOSE： To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontie flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration. METHODS： Two hundred and fifty Uyghur and 250 Han patients with chronic apical periodontitis in their incisor, canine and premolar were collected, and randomly divided into 2 groups： experimental group and control group. After single-visit root canal therapy, Uyghur patients in the experimental group （UEG） and Han patients in the experimental group （HEG） took ihuprofen capsules according to the drug instructions; while Uyghur patients in the control group （UCG） and Hart patients in the control group（HCG） took placebo capsules. Both doctors and patient kept blind from the drug capsules and group of the patients. The incidence, degree of endodontic Flare-up at 6, 12, 24, 48, 72 hours and 1 week after root canal therapy were recorded and analyzed by χ2 test using SPSS11.0 software package. RESULTS： During the experiment, the incidence of E flare-up in Uygur patients was higher than in Han patients; the incidence of E flare-up in different groups in orders from high to low was： UCG〉HCG〉UEG〉HEG. Chi-square test showed that there were significant differences between the two groups. In view of time distribution, most of flare-up happened between 24- 48 hours after root canal therapy with the highest degree in all 4 groups. Regardless of the incidence or degree of flare-up, HEG and HCG were significantly greater than UEG and UCG. CONCLUSIONS： Ibuprofen can reduce and prevent flareup for both Uyghur and Han patients, but it has better effect on Han patients.

关 键 词：慢性根尖周炎 根管治疗后疼痛 布洛芬 维吾尔族 

分 类 号：R781.341[医药卫生—口腔医学]