抗精神病药物所致恶性综合征15例临床分析  

Clinical analysis of 15 cases of malignant syndrome caused by antipsychotic drugs

作　　者：李英亭[1] 李思媛[1] 张炜[1] 

机构地区：[1]石家庄市第八医院,河北石家庄050081

出　　处：《临床医药文献电子杂志》2017年第12期2184-2184,2186,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的主要研究抗精神病药物所致恶性综合征的临床特征。方法选取我院于2015年4月—2016年4月间收治的15例抗精神病药物所致恶性综合征患者,对其临床特点进行研究与分析。结果抗精神病药物所致恶性综合征患者的临床表现主要为意识障碍、发热、心动过速、肌强直等,在对患者实施停用药物、针对性治疗后,患者均获得痊愈。抗精神病药物所致恶性综合征患者发病前表现为运动神经兴奋、进食差,并且夏季发病患者率较多。结论抗精神药物所致恶性综合征的临床特点,因此在临床上要予以高度重视,在发现患者出现类似病症后,需要及时采取针对性治疗,为进一步保证患者预后奠定基础。Objective to research the clinical characteristics of malignant syndrome caused by antipsychotic drugs. Methods to choose the hospital in April 2015-April 2016 15 patients with malignant syndrome caused by antipsychotic drugs, research and analysis on its clinical feature. Results the clinical manifestations of the patients with malignant syndrome caused by antipsychotic drugs mainly for the disturbance of consciousness, such as fever, tachycardia, myotonia, after stop using drugs, targeted therapy for patients, all patients get recovered. Patients with malignant syndrome caused by antipsychotic drugs before the onset of motor nerve excitement, eat- ing is poor, and the incidence rate of patients more in summer. Conclusion the clinical characteristics of malignant syndrome caused by antipsychotic, so pay highly attention to clinically, after found that patients with similar symptoms, to take timely targeted treatment, the prognosis of patients with in order to further ensure that lay the foundation.

关 键 词：抗精神病药物 恶性综合征 临床分析 

分 类 号：R749.053[医药卫生—神经病学与精神病学]