四联药物联合治疗慢性胃炎的疗效观察  

The effects of quadruple drug therapy on chronic gastritis

作　　者：余天奉 

机构地区：[1]广州市南沙区鱼窝头医院内科,广东511458

出　　处：《中国临床新医学》2017年第4期368-370,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨四联药物联合治疗慢性胃炎的疗效。方法选取2014-02~2016-02收治的64例慢性胃炎患者作为研究对象,随机分为对照组和观察组各32例。分别给予单一药物(阿莫西林)和四联药物(阿莫西林、呋喃唑酮、奥美拉唑、胶态果胶铋)治疗,对比两组患者临床疗效和不良反应发生率。结果观察组显效14例,有效15例,无效3例;对照组显效8例,有效13例,无效11例,观察组疗效优于对照组(P<0.05)。观察组不良反应发生率(6.25%)明显低于对照组(25.00%)(P<0.05)。结论阿莫西林、呋喃唑酮、奥美拉唑、胶态果胶铋四联药物联合治疗慢性胃炎,具有疗程短、剂量小、不良反应发生率低等优点,临床疗效显著,值得推广应用。Objective To evaluate the effects of drug therapy on chronic gastritis. Methods Sixty-four patients with chronic gastritis treated in our hospital from February 2014 to February 2016 were selected as the research subjects and were randomly divided into the control group and the observation group, with 32 cases in each group. The control group was given single drug amoxicillin and the observation group was given quadruple drug therapy including amoxicillin, furazolidone, omeprazole and colloidal bismuth pectin. The clinical efficacy and incidence of adverse reactions were compared between the two groups. Results The efficiency of the observation group was markedly effective in 14 cases, effective in 15 cases and invalid in 3 cases ; The efficiency of the control group was markedly effective in 8 cases, effective in 13 cases and invalid in 11 cases. The total effective rate of the observation group was sig- nificantly higher than that of the control group （ P 〈 0. 05 ） ; The incidence of adverse reactions in the observation group was significantly lower than that in the control group （ 6. 25% vs 25.00% ） （ P 〈 0. 05 ）. Conclusion The quadruple drug therapy is effective on chronic gastritis, with a shorter course of treatment, a smaller dosage, lower price and a lower incidence of adverse reactions.

关 键 词：阿莫西林 呋喃唑酮 奥美拉唑 胶态果胶铋 慢性胃炎 

分 类 号：R573[医药卫生—消化系统]