Utilizing a microfluidic device to enrich and fluorescently detect circulating tumor cells  

作　　者：Ya-Nan Chang Mingyi Zhang Juan Li Kui Chen Weihong Gu Gengmei Xing 

机构地区：[1]CAS Key Laboratory for Biomedical Effects of Nanomaterial & Nanosafety,Institute of High Energy Physics,Chinese Academy of Science

出　　处：《Science Bulletin》2017年第7期453-455,共3页科学通报（英文版）

基　　金：supported by the National Basic Research Program of China(2015CB932100,2013CB932703);the National Natural Science Foundation of China(11405185)

摘　　要：Circulating tumor cells(CTCs)are cancer cells that have propagated from primary tumor sites,spreading into the bloodstream as the cellular origin of fatal metastasis,and to secondary tumor sites.Capturing and analyzing CTCs is a kind of‘‘liquid biopsy'of the tumor that provides information about cancer changes over time and tailoring treatment[1].CTC enrichment and detection remains technologically challenging due to their extremely low concentra-Circulating tumor cells （CTCs） are cancer cells that have propagated from primary tumor sites, spreading into the bloodstream as the cellular origin of fatal metastasis, and to secondary tumor sites. Capturing and analyzing CTCs is a kind of ＂liquid biopsy＂ of the tumor that provides information about cancer changes over time and tailoring treatment.

关 键 词：QDS CELL LINE MCF Utilizing a microfluidic device to enrich and fluorescently detect circulating tumor cells 

分 类 号：R730.4[医药卫生—肿瘤]