临床生物样本库发展及其影响因素分析  

Analysis for the clinical biobanks sustainable development and influence factors

作　　者：李海燕[1,2] 倪明宇[1] 王晓民[1] 

机构地区：[1]首都医科大学卫生管理与教育学院,北京100069 [2]首都医科大学科技处

出　　处：《中华医学科研管理杂志》2017年第2期85-89,共5页Chinese Journal of Medical Science Research Management

基　　金：北京市科委计划项目（D13110700530000,D131100005313002）

摘　　要：目的对临床生物样本库的发展及其影响因素进行分析，为临床生物样本库的建设发展提供参考依据。方法通过回顾北京重大疾病资源库建设发展过程，并结合国内外的相关文献报道，对临床生物样本库的发展和影响因素进行定性分析。结果随着生物样本库的迅速发展，随之带来的是样本库的运行成本不断增大，也涌现出了各种问题，其可持续发展引起了越来越多的关注，受共享应用、资金、人员队伍、信息化能力、战略需求和政策等方面影响。结论临床生物样本库的运行和可持续发展面临着越来越多的挑战。应该更多的是基于研究需求出发而进行临床样本库的设计和建设，同时考虑利益相关者的利益需求，以提高样本库的效益，降低成本，确保样本库的可持续发展。Objective Analysis the clinical biobanks sustainable development and influence, and give some advices for the development of clinical biobanks. Methods By review the development of Beijing Biobank of Clinical Resources, and combined with the related literature, we analysis the clinical biobanks sustainable development and influence. Results With the rapid development of the biobank, its sustainable development has attracted more and more attention, and is influenced by sharing, funds, staff, information, strategies and policies. Conclusions The sustainable development of clinical biobanks is facing more and more challenges. For the sustainable development of clinical biobanks, the constructer should be focus on the requirement from the research, and pay attention to the inter ests of stakeholders.

关 键 词：生物样本库 可持续发展 样本共享 精准医学 

分 类 号：R-05[医药卫生]