氟代脱氧葡萄糖PET/CT在胆囊癌术前评估中的价值  

The value of ^(18)F-FDG PET/CT in preoperative assessment of gallbladder carcinoma

作　　者：张晨波 庞丽芳[2] 薄晓波[1] 王瑶婕 王杰[1] 王越琦[1] 

机构地区：[1]复旦大学附属中山医院普通外科,上海200032 [2]复旦大学附属中山医院核医学科,上海200032

出　　处：《中国临床医学》2017年第2期210-213,共4页Chinese Journal of Clinical Medicine

基　　金：国家自然科学基金(81502004);上海市科学技术生物委员会生物医药领域项目(16411952000)~~

摘　　要：目的:探讨氟代脱氧葡萄糖(18 F-FDG)正电子发射计算机断层显像(PET/CT)在胆囊癌患者术前评估中的价值。方法:回顾分析复旦大学附属中山医院术前诊断为胆囊癌并接受术前PET/CT检查的59例患者的临床资料。统计分析PET/CT对胆囊癌的肿瘤定性、淋巴转移和远处转移的诊断价值。结果:59例患者中,55例术后病理证实为胆囊癌,1例胆总管癌,3例胆囊炎。PET/CT对胆囊癌诊断的灵敏度为90.9%,对淋巴转移诊断的灵敏度和特异度为61.5%和72.3%,对远处转移的诊断灵敏度和特异度为66.7%和91.1%。最大摄取值(SUVmax)值在不同肿瘤分期、淋巴转移和远处转移中差异无统计学意义。结论:PET/CT对胆囊癌的术前评估,尤其是淋巴转移和远处转移评估具有重要的价值,但在不同分期肿瘤中仍有待进一步研究。Objective： To explore the value of 18F - FDG PET/CT in preoperative assessment of patients with gallbladder carcinoma. Methods ： The clinical data of 59 patients whowere preliminarily diagnosed as gallbladder cancer and who accepted PET/CT preoperatively in Zhongshan hospital, Fudan university were retrospectively analyzed. The diagnostic value of PET/CT in the identification of tumor, lymph node metastasis and distant metastasis of gallbladder cancer was statistically analyzed. Results： Of the 59 patients,55 patients were postoperatively pathologically confirmed as gallbladder cancer,1 patient as cholangiocarcinoma and 3 patients as inflammatory disease of gallbladder. The sensitivity of PET/CT in tumor identification was 90. 9%,while the sensitivity and specificity of PET/CT in the diagnosis of lymph node metastasis and distant metastasis were 61. 5% and 72. 66 . 7% and 91. 1% ,respectively. SUVmax value showed no statistical differencein tumor staging,lymph node metastasis and distant metastasis. Conclusions： PET / CT is of important value in the preoperative evaluation of gallbladder cancer,especially in the assessment of lymph node metastasis and distant metastasis. However,its value in tumor staging remains to be further evaluated.

关 键 词：胆囊癌 正电子发射型电子计算机断层 肿瘤分期 

分 类 号：R735.8[医药卫生—肿瘤]