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出 处:《中华消化外科杂志》2017年第5期446-449,共4页Chinese Journal of Digestive Surgery
基 金:国家自然科学基金(30770982)
摘 要:食管胃结合部腺癌(AEG)的定义、分期及治疗一直存在诸多争议。手术是AEG主要治疗手段.临床上根据AEG不同分型,选择不同手术方式。然而单纯手术治疗效果常差强人意。新辅助同步放化疗和围术期化疗可改善AEG患者生存情况。第8版美国癌症联合会(AJCC)TNM食管癌分期系统提供了简化的AEG2cm原则。并新增了其cTNM、ypTNM分期,提高了该版分期系统的临床实用性。The definition, staging and optimal treat- ment of adenocarcinoma of esophagogastrie junction (AEG) have long been in controversy. Surgery is still the primary treat- ment for resectable AEG, and surgical procedures depend on its classifications. However, the efficacy of surgery alone is barely satisfactory. Neoadjuvant ehemoradiotherapy and perioperative chemotherapy can improve the survival of patients. Simplified "2 era" principle is presented in the 8th edition of American Joint Committee on Cancer for TNM staging system of esophageal cancer. In addition, the new edition provides clinical staging and pathologic staging after neoadjuvant therapy, improving the clini- cal practicability of new staging system.
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