新型香料环丙香豆素的合成及加香应用研究  

Study on Synthesis and Application of a Novel Aroma Chemical Cyclopropylcoumarin

作　　者：邬帅帆 徐晓炯 崔秀明 

机构地区：[1]华宝(上海)管理有限公司,上海201821

出　　处：《香料香精化妆品》2017年第2期20-22,共3页Flavour Fragrance Cosmetics

摘　　要：以香豆素为原料通过Corey-Chaykovsky反应一步合成了环丙香豆素。通过~1H NMR、^(13)C NMR、HRMS对产物进行了表征,确认了化合物的结构,并对反应条件进行了优化。进一步对产物的香气进行了评价,在卷烟中添加环丙香豆素能明显改善烟气及香气品质。Cyclopropylcoumarin was synthesized via one-step Corey-Chaykovsky reaction using coumarin as raw material. The structure of the final compound obtained was confirmed by ^1H NMR、^13C NMR、HRMS spectra. Several reaction parameters were optimized to enhance the final yield. Furthermore, its application effects in tobacco were studied and the results proved that it can improve the smoking and flavor quality.

关 键 词：Corey-Chaykovsky反应 香豆素环丙化 合成 

分 类 号：TS264.3[轻工技术与工程—发酵工程]