急性期血压对脑梗死患者认知功能的影响  

The effect of acute blood pressure on cognitive function in patients with cerebral infarction

作　　者：李军[1] 

机构地区：[1]北京市垂杨柳医院神经内科,北京100022

出　　处：《热带医学杂志》2017年第4期523-525,共3页Journal of Tropical Medicine

摘　　要：目的探讨急性期血压对脑梗死患者认知功能的影响。方法选取2013年4月到2015年4月于北京市垂杨柳医院接受治疗的发病24 h内入院的脑梗死患者132例,按照住院后前3 d平均收缩压水平将其分为A组30例、B组61例、C组41例,其中A组平均收缩压90~130 mm Hg,B组130~160 mm Hg,C组大于160 mm Hg,三组患者分别在入院24 h、入院15 d、病后6个月采用美国国立卫生院神经功能缺损评分(NIHSS量表)、蒙特利尔认知评估(MoCA)量表对患者神经、认知功能进行评价,比较三组患者在神经功能缺失程度和认知功能上的差距。结果三组患者入院24 h、入院15 d、发病6个月认知功能评分、神经功能评分比较差异有统计学意义;A、C组入院24 h、入院15d、发病6个月认知功能评分低于B组,神经功能评分高于B组,差异均有统计学意义(P<0.05)。结论处于一定血压区间对脑梗死患者认知功能有保护作用。Objective To explore the effect of acute stage blood pressure on cognitive function in patients with cerebral infarction. Methods 132 cases were selected from April 2013 to April 2015 to receive the treatment within 24 hours of admission in our hospital with acute cerebral infarction. According to the average systolic blood pressure levels after 3 days of admission,patients were divided into group A,30 cases,group B,61 cases,and group C,41 cases;the mean systolic blood pressures for group A,B and C were 〈130 mmHg,130-160 mmHg and 〉160 mmHg,respectively.The neurological deficit function and the cognitive function of the patients were evaluated at 24 hours of admission,15 days of admission,6 months after curing by the National Institutes of Health（NIHSS） and the Montreal Mental Assessment（Mo CA） scale. The neurological deficits and cognitive function were compared between the three groups. Results The cognitive function scores and neurological function scores of patients admitted to hospital for 24 h,15 days of admission,6 months after curing among the three groups had significant differences（P〈0.05）. The scores of cognitive function were significantly lower in group A and group C than those in group B（P〈0.05）. The scores of neurological function were significantly higher in group A and group C than those in group B（P〈0.05）. Conclusion Keeping in a certain range of blood pressure could have a protective effect on the cognitive function of patients with cerebral infarction.

关 键 词：急性期 血压 脑梗死 神经功能 认知功能 

分 类 号：R743.9[医药卫生—神经病学与精神病学]