不同TOAST亚型脑卒中患者动脉硬化负担分级比较  

Comparison of the atherosclerotic burden in stroke patients with different TOAST subtypes

作　　者：孔维霞[1] 杨青[1] 李蔚[1] 周英[1] 刘会苗[1] 王敏[1] 

机构地区：[1]郑州大学第五附属医院超声医学科,郑州450052

出　　处：《中国实用神经疾病杂志》2017年第9期14-17,共4页Chinese Journal of Practical Nervous Diseases

摘　　要：目的按照TOAST分型标准对急性脑梗死患者进行病因学分型,并评价各类型患者的动脉硬化负担分级。方法选取2014-01—2016-05我院收治的急性脑梗死患者160例,并对其临床资料进行回顾性分析;按照TOAST标准进行病因分型,并根据动脉硬化负担分级对各亚型卒中患者进行分级评价,比较各亚型卒中患者的动脉硬化负担分级。结果 TOAST分型结果:心源性栓塞型(CE)24例(15.38%),大动脉粥样硬化型(LAA)54例(34.62%),小动脉闭塞型(SAO)28例(17.59%),其他明确病因型(ODC)20例(12.82%)及不明原因型(UND)30例(19.23%);动脉硬化负担分级结果:心源性栓塞型患者、大动脉粥样硬化型患者与小动脉闭塞型患者的动脉硬化负担分级程度高于其他明确病因型与不明原因型,差异有统计学意义(P<0.05)。结论心源性栓塞型、大动脉粥样硬化型与小动脉闭塞型患者的病因均与血管性因素有关,通过动脉硬化负担分级有利于血管性脑卒中患者的病因诊断。Objective The acute cerebral infarction patients were divided into subgroups according to TOAST classification criteria. Difference in atherosclerotic burden（AB）was evaluated in stroke patients with different TOAST subtypes. Methods We retrospectively analyzed the clinical data of 160 acute cerebral infarction patients from January 2014 to May 2016 in our hospital. All patients were divided into subgroups according to TOAST classification criteria, and were also evaluated with the classification of AB. Results The TOAST classification results showed that there were 24（15.38%）cardiogenic embolism（CE）patients, 54 （34.62%） large artery atherosclerosis（LAA） patients, 28 （ 17.59 %） small artery occlusion（SAO） patients, 20 （ 12.82%） other clear etiology（ODC） patients and 30 （19.23%）unknown causes（UND）patients. AB classification showsed that the scores were higher in patients of cardiogenic embolism, large artery atherosclerosis and small artery occlusion than that in other type patients （P〈0.05）. Conclusion The etiology of patients with cardiac embolism,large artery atherosclerosis and small artery occlusion is related to vascular factors. AB is beneficial to the diagnosis of cerebral apoplexy patients.

关 键 词：脑卒中 病因 TOAST分型 动脉硬化负担 

分 类 号：R743.3[医药卫生—神经病学与精神病学]