雄性生殖道衣原体感染动物模型研究进展  

Animal models of male genital tract chlamydia infection:An update

作　　者：涂响安[1] 吕坤龙[1] 邓春华[1] TU Xiang-an LU Kun-long DENG Chun-hua(Department of Urology, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China)

机构地区：[1]中山大学附属第一医院泌尿外科,广东广州510080

出　　处：《中华男科学杂志》2017年第5期387-391,共5页National Journal of Andrology

基　　金：国家自然科学基金(81471449);广东省科技计划项目(2016A020218007)~~

摘　　要：沙眼衣原体感染是男性最常见的性传播疾病之一,然而有关衣原体在男性生殖道感染的致病和免疫机制的研究却十分有限。疾病动物模型在研究疾病的致病机制、疾病过程及其治疗转归等方面发挥着十分重要的作用。雄性生殖道衣原体感染模型数量较少并且不是很完善,本文就其衣原体种类、动物种类、感染途径、感染器官、感染过程、生殖影响等方面展开讨论,为男性生殖道衣原体感染的进一步研究提供帮助。[ Abstract] Chlamydia trachomatis infection is one of the most prevalent sexually transmitted diseases in males and studies on its pathogenic and immunologic mechanisms are rather limited. Animal models play an important role in studying the pathogenesis, course and treatment of human diseases, and those of male genital tract chlamydial infection are relatively few and not well developed. This ar- ticle focuses on the chlamydia species, animal species, infection route, infected organ, and infection process of chlamydia, as well as its impact on reproduction, aiming to provide some help for further studies of male genital tract chlamydial infection.

关 键 词：沙眼衣原体 衣原体 雄性 生殖道 感染 动物模型 

分 类 号：R-332[医药卫生] R697