乳果糖与茵陈合剂对轻微型肝性脑病的治疗作用比较  

Comparison of lactulose and Yinchen mixture in the treatment of minimal hepatic encephalopathy

作　　者：王玉富 

机构地区：[1]河南驻马店市中医院肝胆脾胃科,河南驻马店463000

出　　处：《临床研究》2017年第4期54-55,共2页Clinical Research

摘　　要：目的观察乳果糖与菌陈合剂对轻微型肝性脑病（MHE）的治疗作用.方法将88例MHE患者随机分成乳果糖组和菌陈合剂组.乳果糖组患者应用乳果糖口服,菌陈合剂组患者应用菌陈合剂口服.治疗前、后分别对两组患者进行数字连接试验（NCT-A）、划线试验时间检查及血氨、丙氨酸氨基转移酶（ALT）检测.结果治疗前,两组患者的NCT-A、划线试验时间及血氨、ALT比较,差异无统计学意义（P〉0.05）;治疗后,两组的NCT-A、划线试验时间及血氨、ALT较治疗前降低（P〈0.05）,且菌陈合剂组的NCT-A、划线试验时间及血氨、ALT均低于乳果糖组（P〈0.05）.结论菌陈合剂用于MHE的治疗,效果较好,值得推广.Objective To observe the therapeutic effect of lactulose and Yinchen mixture in the treatment of minimal hepatic encephalopathy （MHE）. Methods Eighty-eight cases of patients with MHE were randomly divided into lactulose group and Yinchen mixture group. The lactulose group was treated with lactulose, while the Yinchen mixture group was treated with Yinchen mixture. Before and after treatment, the patients of the two groups were tested by the number connection test （NCT- A）, scribe test and blood ammonia, alanine aminotransferase （ALT） detection. Results Before treatment, there were no significant differences on the NCT-A, time of scribe test, blood ammonia and ALT between the two groups （P〉0.05）. After treatment, the NCT-A, time of scribe test, blood ammonia and ALT of the two groups were decreased （P〈0.05）, and the NCT- A, time of scribe test, blood ammonia and ALT detection of the Yinchen mixture group were lower than those of the lactulose group （P〈0.05）. Conclusion The effect of Yinchen mixture on MHE is remarkable, which is worthy of promotion.

关 键 词：肝性脑病 乳果糖 菌陈合剂 

分 类 号：R747.9[医药卫生—神经病学与精神病学]