丙氨酸氨基转移酶升高老年人的临床特征及与超声诊断脂肪肝的相关性  

Clinical characteristics of the aged with elevated alanine aminotransferase and the correlation with the ultrasonic diagnosis of fatty liver

作　　者：董愉[1] 刘淑华[1] 

机构地区：[1]江苏江阴人民医院,江苏江阴214400

出　　处：《临床研究》2017年第4期183-184,共2页Clinical Research

摘　　要：目的分析丙氨酸氨基转移酶升高的老年人的临床特征,并探究其与超声诊断脂肪肝的相关性.方法抽取2015年5月至2016年5月在本院接受体检显示丙氨酸氨基转移酶升高的60岁以上老年人共90例作为研究对象,对其进行腹部B超检查,按照有无脂肪肝分成两组,观察组为脂肪肝患者（40例）,对照组为非脂肪肝者（50例）,对比分析两组的临床特征以及实验室检测结果.结果观察组患者体质量（BMI）、糖尿病史的人数比例显著高于对照组（P〈0.05）;两组患者的高血压史、高血脂史的人数比例比较无显著性差异（P〉0.05）.观察组甘油三脂水平与对照组相比,明显较高,有显著性差异（P〈0.05）;两组患者的丙氨酸氨基转移酶、谷草转氨酶、谷胺酰转肽酶、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、空腹血糖、尿酸指标比较,均无显著性差异（P〉0.05）.回归性分析结果显示,BMI异常及糖尿病史是丙氨酸氨基转移酶升高的老年人脂肪肝的独立危险因素.结论高BMI和糖尿病史可用于丙氨酸氨基转移酶升高老年人超声下脂肪肝的预测.Objective To investigate the clinical characteristics of the aged with elevated alanine aminotransferase and the correlation with the ultrasonic diagnosis of fatty liver. Methods Ninety cases of the aged with elevated alanine aminotransferase whose age were greater than 60 in our hospital from May 2015 to May 2016 were divided into observation group （ n=40, fatty liver） and control group （ n=50, without fatty liver） according to the abdominal ultrasonic examination. The clinical characteristics and laboratory test results of the two groups were compared. Results The BMI ,proportion of diabetes history, triglycerides of the observation group were significantly higher than those of the control group （P 〈0.05）, and there was no significantly differences in proportion of high blood pressure, proportion of high cholesterol,alanine aminotransferase, aspertate aminotransferase, glutamyl transpeptidase, total cholesterol, high -density lipoprotein cholesterol, low density lipoprotein cholesterol, fasting blood glucose, uric acid between the two groups （P 〉0.05）. Conclusion BMI and diabetes history can be used to forecast fatty live under ultrasonic.

关 键 词：老年人 丙氨酸氨基转移酶 临床特征 超声诊断 脂肪肝 

分 类 号：R575.5[医药卫生—消化系统]