甲状腺炎性肌纤维母细胞瘤1例  

Inflammatory myofibroblastic tumour of thyroid:a case report

作　　者：张彩霞[1] 刘庚勋[2] 刘阳云[1] 江文[1] 曹杭[1] 陈琼[1] 常恩格 张纪帅[1] 邬书本[1] 赵花香 

机构地区：[1]湖南师范大学医学院第二附属医院解放军第一六三医院耳鼻咽喉科,长沙410003 [2]湖南师范大学医学院第二附属医院解放军第一六三医院病理科

出　　处：《临床耳鼻咽喉头颈外科杂志》2017年第9期720-721,共2页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：1病例报告 患者,女,64岁,因颈部肿物4个月于2016年5月5日入院。患者自诉2016年1月无意中触及颈前一绿豆大小肿物,除按压时稍感疼痛外无其他不适,未行处理。肿物逐渐增大,压痛较前明显,进食时伴肿物胀痛,偶有胸闷、心慌,遂来我院门诊。门诊以＂甲状腺肿物性质待查（左）＂收入。A elderly woman patient,with a unclear boundary,solid,smooth surface,moderately active mass that estimated 0.4 cm at its greatest diameter in the left lobe of thyroid.Ultrasonography revealed a hypoechoic mass in the left lobe and Computed Tomography showed a 38mm×25mm×23mm oval lesion with uniform density in the left lobe also.The surgical findings revealed tumor located in the inner side of left thyroid lobe near the isthmus,with unclear boundary.Pathological examination showed unclear boundaries between thyroid and tumor,the tumor cells attack into the muscle tissue,braided/fascicles spindle shaped or star shaped myofibroblasts cells in the tumor area with myxedema inflammatory background and the lesion did not have any mitotic figures.Immunohistochemical analysis indicated that the spindle cells were positive for Vim,ACT,SMA,Bcl2 and ClyD1,and focal lesion histiocytes showed focal positive for CD68,CK and S-100,but negative for DES,Mgo,CD99,CD34,CD117,IgG4,ALK-1.The pathological diagnosis supports inflammatory myofibroblastic tumor of thyroid.Imaging and immunohistochemistry and others are useful in differential diagnosis.

关 键 词：炎性肌纤维母细胞瘤 甲状腺 

分 类 号：R739.6[医药卫生—肿瘤]