卒中后癫痫研究进展  

Research Progress of Post-stroke Epilepsy

作　　者：孙立超[1] 朱战鹏[2] 林卫红[3] 

机构地区：[1]吉林大学第一医院急诊内科,长春1130021 [2]吉林大学第一医院神经外科 [3]吉林大学第一医院神经内科

出　　处：《中国卒中杂志》2017年第4期327-331,共5页Chinese Journal of Stroke

摘　　要：卒中与癫痫为神经系统最常见疾病,二者关系密切。卒中后癫痫(post-stroke epilepsy,PSE)为卒中常见并发症,是老年人首发癫痫最常见病因,发作类型多样,其发生与卒中类型、部位密切相关,严重影响患者生活质量及预后。目前研究发现离子通道、神经递质、遗传等多个因素参与PSE的发生发展。本文就PSE定义、流行病学、发病机制、临床特点及治疗的最新进展做一综述。Stroke and epilepsy are the most common diseases in the nervous system, which associate with each other closely. Post-stroke epilepsy （PSE） is a common complication of stroke, which has become the most vital cause of the first onset epilepsy in the seniors. PSE has various types of seizure, which links to the type of stroke and lesion location closely. PSE results in higher morbidity and disability rate and seriously affected the quality of life and prognosis. Recent studies found that many factors such as ion channel, neurotransmitter and genetics participate in the origination and development of PSE. This review mainly aims to provide the definition, epidemiology, mechanisms, clinical features and therapy of PSE.

关 键 词：卒中 癫痫 发病机制 治疗 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R743.3[医药卫生—临床医学]