机构地区:[1]泰山医学院公共卫生学院流行病学教研室,山东泰安271016 [2]上海市黄浦区疾病预防控制中心慢性病防治科,上海200023 [3]复旦大学附属妇产科医院临床流行病学研究室,上海200011
出 处:《中华肿瘤防治杂志》2017年第3期151-155,共5页Chinese Journal of Cancer Prevention and Treatment
基 金:黄浦区优秀学科带头人项目(HPXD-05)
摘 要:目的喉癌是常见的头颈部恶性肿瘤,国内有关喉癌的流行病学研究报道较少,本研究分析上海市卢湾区2004-2011年喉癌的发病情况和死亡情况,为制订喉癌的预防和干预措施提供依据。方法系统整理2004-01-2011-12上海市肿瘤登记报告中卢湾区户籍人群喉癌发病和死亡资料并进行统计分析,计算喉癌发病率及死亡率,并进行标化。分析发病率和死亡率变化趋势。结果 2004-2011年卢湾区新发喉癌病例共68例,占全区同期新发恶性肿瘤的0.65%。喉癌年均粗发病率为2.72/10万,中标发病率为1.14/10万,世标发病率为1.41/10万。男性喉癌年均粗发病率为5.17/10万,中标发病率为2.19/10万,世标发病率为2.69/10万;女性喉癌年均粗发病率为0.32/10万,中标发病率为0.15/10万,世标发病率为0.20/10万。登记报告喉癌死亡病例共47例,占全区同期恶性肿瘤死亡例数的0.71%。喉癌年均粗死亡率为1.88/10万,中标死亡率为0.58/10万,世标死亡率为0.79/10万。男性喉癌年均粗死亡率为3.31/10万,中标死亡率为1.03/10万,世标死亡率为1.38/10万;女性喉癌年均粗死亡率为0.47/10万,中标死亡率为0.22/10万,世标死亡率为0.32/10万。男性喉癌发病率和死亡率均高于女性。8年间男性喉癌的发病率和死亡率波动较大,而女性的发病率和死亡率则极低。随着年龄增大,喉癌发病率和死亡率明显上升。结论上海市卢湾区居民2004-2011年喉癌发病率和死亡率均高于全国肿瘤登记地区发病和死亡水平,提示应以社区为基础开展积极有效的防治工作。OBJECTIVE Laryngeal cancer is a common head and neck cancer,and there are few epidemiological studies on laryngeal carcinoma in China.The objective of this study was to analyze the incidence and mortality of laryngeal cancer among residents in Luwan district of Shanghai from 2004 to 2011for providing evidences for prevention and intervention of laryngeal cancer.METHODS The data of laryngeal cancer in permanent residents of Luwan district were collected from the database of cancer registration and management system in Shanghai.The incidence and mortality of laryngeal cancer were calculated and normalized.The temporal trend in the incidence and mortality of laryngeal cancer were assessed.RESULTS A total of 68 cases of laryngeal cancer were diagnosed from January 2004 to December 2011,accounting for 0.65% of the total patients with malignant diseases.The average annual crude incidence rate of laryngeal cancer was 2.72/105,age-standardized incidence rate by Chinese standard population(ASIRC)was 1.14/105 and age-standardized incidence rate by world standard population(ASIRW)was 1.41/105.Average annual crude incidence rates of males and females were 5.17/105 and 0.32/105,ASIRC were 2.19/105 and 0.15/105 and ASIRW were 2.69/105 and 0.20/105respectively.A total of 47cases died of laryngeal cancer during this period,accounting for 0.71%of the total patients with malignant diseases.The average annual crude mortality rate of laryngeal cancer was 1.88/105,and age-standardized mortality rate by Chinese standard population(ASMRC)and by world standard population(ASMRW)were 0.58/105 and0.29/105.Average annual crude mortality rates of males and females were 3.31/105 and 0.47/105 respectively,ASMRC were 1.03/105 and 0.22/105,and ASMRW were 1.38/105 and 0.32/105 respectively.Both the incidence and mortality of male laryngeal cancer were significantly higher than that of females.During these 8years,there were some fluctuations of laryngeal cancer incidence and mortality for males,while both the incidence and mortalit
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