棘阿米巴性角膜炎的手术治疗进展  

The surgical treatment of acanthamoeba keratitis

作　　者：张亚丽 刘丽梅 张少斌 

机构地区：[1]潍坊眼科医院,261041

出　　处：《国际眼科纵览》2017年第2期122-125,共4页International Review of Ophthalmology

摘　　要：棘阿米巴性角膜炎是由棘阿米巴原虫感染引起的慢性、进行性、疼痛性角膜溃疡，也是一种严重的致盲性眼病。棘阿米巴性角膜炎与配戴角膜接触镜、接触污染的水源和角膜外伤等有关。对棘阿米巴性角膜炎目前治疗以药物为主，药物治疗无效时应及时给予手术治疗。角膜病灶切除及局部烧灼、角膜病灶切除联合球结膜瓣遮盖术或羊膜移植术、角膜移植术等治疗方法在临床均有应用，新兴的角膜胶原交联治疗的临床应用更为棘阿米巴性角膜炎的治愈提供了新的希望。Acanthamoeba keratitis is caused by acanthamoeba protozoa infection, which usually presents as a chronic, progressive and painful corneal ulcer. It is also a serious blindness leading eye disease. Acanthamoeba keratitis is related to wearing corneal contact lens, pollution of water source and corneal trauma. For the treatment of acanthamoeba keratitis, the first choice is medicine. Timely surgical treatment should be given when drug therapy fails. The surgical treatments include corneal lesion resection, corneal local burn, corneal lesion resection combined with conjunctival flap covering or amniotic membrane transplantation, corneal transplantation, etc. The clinical application of new corneal collagen cross-linking therapy gives more hope for cure of acanthamoeba keratitis.

关 键 词：棘阿米巴 角膜炎 胶原交联 

分 类 号：R779.6[医药卫生—眼科]