合并脑微出血的脑梗死病人出血转化的风险性研究  

Relationship between hemorrhagic transformation after acute cerebral infarction and cerebral microbleed

作　　者：鲁建华[1] LU Jian-hua(Department of Neurology, Xianning Central Hospital, the First Hospital Affiliated to Hubei University of Science and Technology ,Xianning 437000, Chin)

机构地区：[1]咸宁市中心医院湖北科技学院附属第一医院神经内科,湖北省咸宁市437100

出　　处：《实用老年医学》2017年第5期484-487,共4页Practical Geriatrics

摘　　要：目的探讨合并脑微出血(cerebral microbleed,CMB)的脑梗死病人急性期和恢复期出血转化的风险及可能原因。方法收集我院合并脑CMB的脑梗死病人160例(有CMB组),以及无CMB的脑梗死病人180例(无CMB组),通过比较2组急性期和恢复期出现脑出血的不同发生率,探讨CMB对脑梗死出血转化的影响。结果在脑梗死急性期病人中,2组出血的发生率差异无统计学意义(P>0.05);而对于恢复期的病人,有CMB组病人出血的发生率较高(P<0.05)。恢复期服用阿司匹林病人中,合并CMB病人脑出血的发生率明显高于无CMB组(16.3%比6.7%,P<0.05)结论 CMB可增加脑梗死恢复期病人出血的发生率,尤其是那些服用阿司匹林的病人。CMB可能是一种逐渐进展的脑微血管病。Objective To investigate the incidence rate and risk factors of hemorrhagic transformation after acute cerebral infarction during acute phase and convalescence phase. Methods180 patients without cerebral microbleed（ CMB） were enrolled as non-CMB group,and 160 patients with CMB were selected as CMB group. The incidence rate in different stage were compared between two groups,and the effect of CMB on hemorrhage transformation in patients with cerebral infarction was observed. Results There was no significant difference in the incidence rate of hemorrhagic transformation at acute phase between two groups（ P〉 0. 05）. But at convalescence phase,the incidence rate of hemorrhagic transformation in CMB group was significantly higher than that in non-CMB group（ P〈0. 05）. Conclusions CMB may increase the incidence rate of hemorrhagic transformation in patients with cerebral infarction during convalescence phase,especially for those patients who are taking aspirin.CMB is likely to be a gradual progress of cerebral microvascular disease.

关 键 词：脑梗死 脑微出血 出血转化 

分 类 号：R743.3[医药卫生—神经病学与精神病学]