神经导管治疗周围神经损伤  

Nerve conduits in treatment of peripheral nerve injury

作　　者：曾海涛[1] 刘世清[1] 吴飞[1] 邱波[2] 何启艇 

机构地区：[1]武汉大学人民医院创伤显微外科,湖北武汉430060 [2]武汉大学人民医院骨科骨关节外科,湖北武汉430060

出　　处：《职业与健康》2017年第6期831-834,共4页Occupation and Health

基　　金：青年科学基金项目(81301052);湖北省自然科学基金项目(2014CFB207)

摘　　要：近数十年,由于人们对神经导管的研究和应用取得了很大进展,神经导管应用于周围神经损伤修复已成为趋势。神经导管类型可分为生物型导管和合成型导管,又可分为非降解型导管和可降解型导管。研究者们已经探索了空心导管、含神经营养因子支架的材料导管及以雪旺细胞或其干细胞为种子细胞的神经导管。随着神经导管的材料、结构、内含神经营养因子及支持细胞种类的不断更新,神经导管的疗效也逐渐令人满意。今后,神经导管将广泛应用于临床实践,届时有望看到它在神经损伤功能修复方面的预期成果。In recent decades,due to researches and applications of nerve conduits has been made great progress,nerve conduits used in peripheral nerve injury has become a trend. Nerve conduits types can be classified as biological catheter and forming catheter,and can be divided into the degradable catheter and biodegradable catheter. The researchers have explored the hollow catheter,material conduit with neurotrophic factor scaffolds,and nerve conduit with Schwann cells or stem cells as seed cells. As nerve conduits＇ materials,structure,containing neurotrophic factors and types of support cells constantly updated,the curative effect of nerve conduits also gradually is satisfactory. In the future,nerve conduits will be widely applied in clinical practice,and we can expect to see the expected results on the function of nerve injury repair.

关 键 词：周围神经损伤 神经导管 治疗 

分 类 号：R745[医药卫生—神经病学与精神病学]