Low-frequency blood oxygen level-dependent fluctuations in the brain white matter： more than just noise  

作　　者：Gong-Jun Ji Wei Liao Fang-Fang Chen Lei Zhang Kai Wang 

机构地区：[1]Laboratory of Cognitive Neuropsychology, Department of Medical Psychology, Anhui Medical University, Hefei 230000, China [2]Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China [3]Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, China [4]Collaborative Innovation Centre of Neuropsychiatric Disorder and Mental Health, Hefei 230000, China [5]Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei 230032, China

出　　处：《Science Bulletin》2017年第9期656-657,共2页科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China (81401400 to G.J.J.,81471653 to W.L.,31571149,91432301 and 91232717 to K.W.);the Doctoral Foundation of Anhui Medical University (XJ201532 to G.J.J.);Youth Top-notch Talent Support Program of Anhui Medical University (to G.J.J.);the China Postdoctoral Science Foundation (2013M532229 to W.L.);National Basic Research Program of China (2015CB856405,2012CB720704,and 2011CB707805 to K.W.);Anhui Collaborative Innovation Center of Neuropsychiatric Disorder and Mental Health

摘　　要：The spontaneous activity of the blood oxygen level-dependent(BOLD)signal has been demonstrated as a promising way for understanding how the brain intrinsically organized.However,most of these studies focused solely on the spontaneous activity in gray matter(GM)and not on white matter(WM).This isThe spontaneous activity of the blood oxygen level-dependent （BOLD） signal has been demonstrated as a promising way for understanding how the brain intrinsically organized. However, most of these studies focused solely on the spontaneous activity in gray matter （GM） and not on white matter （WM）. This is likely because low-frequency BOLD fluctuations （LFBFs） in GM are related to postsynaptic potential, while the physiological significance of fluctuations in WM is largely unknown [1 ]. Recently, there are increasing evidences implicating the neurobiological significance of LFBFs in WM [2-4]. Here, we further investigated this issue from the perspective of energy consumption.

关 键 词：WM than Low-frequency blood oxygen level-dependent fluctuations in the brain white matter:more than just noise 

分 类 号：R741[医药卫生—神经病学与精神病学]