基于数据挖掘的乙脑急性期中医用药规律研究  

Analysis on Medication Rule in Prescriptions for Epidemic Encephalitis B at Acute Stage Based on Data Mining Technology

作　　者：王一战 王玉贤[2] 苏芮[3] 韩经丹[2] 范吉平[4] 

机构地区：[1]中国中医科学院眼科医院,北京100040 [2]中国中医科学院中医临床基础医学研究所,北京100700 [3]中国中医科学院中医药发展研究中心,北京100700 [4]中国中医科学院,北京100700

出　　处：《辽宁中医杂志》2017年第5期1032-1035,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金："十二五"国家科技重大专项资助项目(2012ZX10004301-001)

摘　　要：目的:探讨乙脑急性期的中医用药特点及规律。方法:计算机检索乙脑急性期中医证治文献,提取医案的中医四诊信息,经过数据标准化处理并建立数据库,运用中医传承辅助系统挖掘其用药规律。结果:共纳入文献205篇,医案257例。核心药物为石膏、知母、金银花、连翘、生地黄、钩藤,核心组合16个,并推演出候选新处方8个。结论:乙脑急性期的中医用药应依据卫气营血辨证选择主药,并遵循"清热、开窍、熄风止痉"三大原则,重视泻下药在清热法中的运用,为临床治疗提供依据和指导。Objective ： To explore the rule of Chinese medicine in treating epidemic encephalitis B at acute stage. Methods ： Perform a systematic search on Chinese medical literature of epidemic encephalitis B at acute stage. Extract TCM clinical information of medical cases. TCM database was formed after standardization. Use TCM inheritance support system to do the statistics analysis. Results ： A total of 205 studies and 257 medical cases were included in the reseach. The core herbs were goldthread, Radix aucklandiae and Radix Paeoniae Alba. Sixteen core combinations and eight new prescriptions were mined from the database. Conclusion：Traditional Chinese medicine of epidemic encephalitis B at acute stage should select main drugs according to Wei - Qi - Ying - Blood theory＂ and follow the principle of clearing heat, inducing resuscitation and relieving convulsion. Purgatives are important for heat clearing therapy. This research can provide a basis and guidance for the clinic.

关 键 词：乙型脑炎 急性期 中医治疗 数据挖掘 关联规则 聚类算法 

分 类 号：R512.32[医药卫生—内科学]