2010—2012年中国农村育龄妇女25-羟基维生素D水平及影响因素分析  

Serum vitamin D levels of Chinese rural women of childbearing age in 2010-2012

作　　者：刘小兵[1] 张宇[1] 毛德倩[1] 卢佳希[1] 陈竞[1] 杨丽琛[1] 朴建华[1] 杨晓光[1] 

机构地区：[1]中国疾病预防控制中心营养与健康所国家卫生计生委微量元素营养重点实验室,北京100050

出　　处：《卫生研究》2017年第3期367-372,共6页Journal of Hygiene Research

基　　金：国家卫生与计划生育委员会(原卫生部)医改重大项目[中国居民营养与健康状况监测(2010-2013年)]

摘　　要：目的了解中国农村18~44岁育龄妇女血清25-羟基维生素D水平及影响因素,为科学评估中国农村育龄妇女维生素D营养状况提供参考数据。方法基于"2010—2012年中国居民营养与健康状况监测",在75个中国农村地区代表性监测点内,共挑选了1520名18~44岁育龄妇女作为研究对象。采用问卷调查收集研究对象基本信息,使用放射免疫法测定血清25-羟基维生素D含量,并依据美国内分泌协会推荐的维生素D标准判定人群维生素D营养状况,应用多因素Logistic回归模型探讨中国农村育龄妇女维生素D缺乏和不足与影响因素的关联性。结果中国农村育龄妇女血清25-羟基维生素D中位数(M_0)含量22.7 ng/mL,P2.5~P97.5范围8.2~42.0 ng/mL。维生素D缺乏率38.7%(血清25-羟基维生素D<20 ng/mL),不足率39.5%(20 ng/mL≤血清25-羟基维生素D<30 ng/mL),充足率21.8%(血清25-羟基维生素D≥30 ng/mL)。多因素Logistic回归模型分析显示,民族、地理分布和家庭年收入对维生素D营养状况的影响具有统计学意义(P<0.05)。结论中国农村18~44岁育龄妇女维生素D缺乏和不足状况比较普遍,特别是少数民族、北方和家庭年收入处于10000~30000元的中国农村育龄妇女维生素D营养状况需要重点关注。Objective To obtain the serum 25-hydroxyvitamin D status for women of child-bearing age aged 18 -44 years from rural areas in China Health and Nutrition Survey 2010- 2012 （CHNS 2010 -2012）. Methods We randomly selected the 1520 representative women of childbearing age from the 75 monitoring spots derived in the CNHS 2010 - 2012. The information of study population were collected using questionnaires and the serum 25-hydroxyvitamin D concentration was determinedusing the RIA kits. The vitamin D nutritional status was classified by the standards suggested by the America Endocrine Society. Multiple Logistic regression analysis was explored the relationship between vitamin D status with the potential relevant factors. Results The median serum 25-hydroxyvitamin D concentration was 22.7 ng/mL ranged from 8.2 to 42.0 ng/mL. The prevalence of vitamin D deficiency was 38.7% , insufficiently 39.5% and sufficiently 21.8%. Multiple Logistic regression analysis showed that nationality, geographical regions and income per capita was the significant. Conclusions The nutritional status of vitamin D in women of child bearing-age is not better in the CNHS 2010 - 2012. We suggest that it should be pay more attention on the women of childbearing age for the minority, north China, family income per year between 10000 and 30000 Yuan.

关 键 词：血清维生素D 育龄妇女 农村 

分 类 号：R153.1[医药卫生—营养与食品卫生学] Q565[医药卫生—公共卫生与预防医学]