神经内镜下经鼻蝶切除垂体瘤手术的临床治疗效果  

Neural endoscopic nasal adjustment in the clinical treatment of pituitary adenoma resection

作　　者：张春林[1] 朱丹婷[1] 黄金生[1] 罗文伟[1] 

机构地区：[1]福建医科大学附属南平第一医院神经外科,福建南平353000

出　　处：《吉林医学》2017年第6期1012-1014,共3页Jilin Medical Journal

摘　　要：目的:对神经内镜下经鼻蝶切除垂体瘤手术的临床治疗效果进行分析探讨。方法:选取28例垂体腺瘤患者,对其全部行神经内镜下经鼻蝶入路垂体腺瘤切除手术,对手术所取得的疗效进行分析探讨。结果:经手术治疗后,有20例(71.43%)患者的肿瘤被全部切除,7例(25.00%)患者的肿瘤近全部切除,1例(3.57%)患者的肿瘤被部分切除。术后共发生5例(17.86%)尿崩症,2例(7.14%)脑脊液鼻漏,3例(10.71%)电解质紊乱,1例(3.57%)垂体分泌功能低下,在采取相应的措施治疗后,并发症全部好转,无一例死亡。术后3个月复查结果显示,视力恢复正常15例(88.24%),头痛缓解8例(80.00%),视野缺损明显好转9例(81.82%)。术前14例PRL升高患者的PRL水平明显下降,术前5例GH升高例患者的GH水平也明显下降,相较治疗前差异均具有统计学意义(P<0.05)。结论:神经内镜下经鼻蝶入路垂体腺瘤手术切除的临床治疗效果显著,安全性高,值得在临床上进一步推广应用。Objective To neural endoscopic nasal adjustment approach the clinical therapeutic effect of pituitary adenoma re-section were analyzed. Method The general information of the selection of the study for between January 2015 and January 2015 our hospital of 28 patients with pituitary adenoma, for all its neural endoscopic nasal butterfly into the way of pituitary adenoma resection surgery, the curative effect of surgery was analyzed. Results After treatment with surgery,20 （71. 4 3 % ） patients were all tumor resection,7 （25. 00% ） patients were nearly all tumor resection, 1 （3. 5 7 % ） patients had partial tumor resection. A to- talof5 （17.86%） cases of postoperative diabetes insipidus, 2 （7.14%） cases of cerebrospinal fluid leak, 3 （10.71%） cases of electrolyte disorder, 1 （3. 57% ） cases of pituitary gland secretion was low,the corresponding measures after treatment, all compli-cations better, 1 had no effect. Review after 3 months,according to the results of visual acuity returned to normal 15 （88. 2 4 % ） cases ,8 （80. 00% ） headache relief, visual field defect improved markedly 9 （81. 8 2 % ） cases. Preoperative 14 cases of patients with elevated PRL,PRL level declined obviously,5 cases of preoperative GH levels rise in patients of GH,compared with before treatment differences were statistically significant （P 〈 0. 05 ）. Conclusion Neural endoscopic nasal adjustment in the clinical treatment of pituitary adenoma resection effect is remarkable, high safety, worthy of further popularization and application in clinic.

关 键 词：神经内镜 垂体瘤 经鼻蝶入路 

分 类 号：R736.4[医药卫生—肿瘤]