磁共振成像技术在眼血-房水屏障中的应用进展  

Application Progress of Magnetic Resonance Imaging in Blood-Ocular Barrier

作　　者：万明军[1] 曹丰[2] 陈辉[2] 王万笔[2] 

机构地区：[1]枣阳市第一人民医院放射科,湖北枣阳441200 [2]襄阳市中心医院湖北文理学院附属医院放射科,湖北襄阳441000

出　　处：《医学综述》2017年第10期2021-2025,共5页Medical Recapitulate

摘　　要：随着动态对比增强磁共振成像(MRI)、磁化传递对比成像等技术的广泛应用,其在眼科中的应用也逐渐增多,且MRI对眼内结构的显示明显优于其他检查手段。目前,MRI的研究热点集中在眼部疾病功能及代谢显像领域,其不仅能精确显示眼部的解剖结构,还能反映眼部药动学、血-房水屏障及房水循环等功能性变化。同时,它还具有无损伤、实时、可重复等优点,是目前眼部疾病检查较为理想的技术。未来,MRI可用于进一步研究青光眼和葡萄膜炎血-房水屏障的改变及其病理生理机制。With the increasing application of dynamic contrast-enhanced magnetic resonance imaging（MRI） and magnetization transfer contrast imaging, the application of MRI in ophthalmology has gradually increased, especially that in the intraocular anatomical structure display, MRI is significantly better than other inspection methods. At present, the research of MRI in ophthalmology is focused on the functional and metabolic imaging,which can not only accurately display the anatomical structure of the eye, but also reflect the change of the eye in the drug pharmacokinetics, blood-aqueous barrier and aqueous humor. These technologies show the advantage of no damage, real-time, repeatable and so on, therefore are ideal technologies for eye disease inspection. In the future, MRI will be used to further study the changes of blood-aqueous barrier and its pathophysiological mechanism in glaucoma and uveitis.

关 键 词：血-房水屏障 磁共振成像 药动学 

分 类 号：R774[医药卫生—眼科]