PI3K-AKT信号通路在后发性白内障中的研究进展  

Progress of PI3K-AKT signaling pathway in posterior capsule opacification

作　　者：邵陈沙 彭燕一[1] 

机构地区：[1]桂林医学院,广西桂林541004

出　　处：《华夏医学》2017年第1期148-152,共5页Acta Medicinae Sinica

摘　　要：后发性白内障(posterior capsule opacification,PCO)是白内障术后最常见的并发症,该病亦是引起术后视力下降的主要原因。近年来随着PI3K-AKT信号通路的深入研究,发现该信号通路在PCO的发生发展中发挥重要作用。现就PI3K-AKT信号通路在PCO发病中作用与机制作一简要综述。Posterior capsule opacification is the most common complication and main cause of eyesight decline after cataract surgery.In recent years,with the research of signal transduction pathway,it was found that PI3K-AKT signaling pathway has played an important role in posterior capsule opacification.This paper briefly reviews the role and mechanism of PI3K-AKT signaling pathway in the pathogenesis of PCO.

关 键 词：PI3K-AKT信号通路 后发性白内障 晶状体上皮细胞 

分 类 号：R776.1[医药卫生—眼科]