磁感应热疗恶性肿瘤技术研究进展  

Advance of magnetic induction hyperthermia for malignant tumor

作　　者：张丽敏[1] 余小刚[1] 贾凯云 吴承伟[1] 张伟[1] 陈震[1] Ravi Silva 

机构地区：[1]大连理工大学工程力学系,大连116024 [2]英国萨里大学先进技术研究院

出　　处：《科技导报》2017年第10期44-51,共8页Science & Technology Review

基　　金：辽宁省自然科学基金项目(2015020198);国家自然科学基金项目(11572080)

摘　　要：磁感应热疗恶性肿瘤是一种基于交变磁场辐照磁介质并通过磁感应产热杀死肿瘤病变组织的新兴技术。20世纪60年代,磁感应热疗技术兴起,围绕提高热疗效果、开发兼具多重疗效的磁性介质和优化温度场分布,开展了大量研究工作,取得了显著效果。本文总结了铁磁热籽、磁流体、磁性脂质体、磁性微晶玻璃、磁性骨水泥等的实验研究与临床应用近期进展,指出进一步提高疗效、优化治疗区热场分布中存在的问题。The magnetic induction hyperthermia for malignant tumor is a kind of new techniques where the heat is generated to kill the tumor lesion tissues through the magnetic media by the application of alternating magnetic fields. Since the development of the inductive heat treatment in the 1960s, many attempts were made to improve the effect of the heat treatment, to develop magnetic mediums with multimodality function and to optimize the temperature field distribution, for achieving numerous excellent results. This paper reviews the experimental studies and clinical applications of several magnetic materials, such as the ferromagnetic thermal seed, the magnetic liquid, the magnetic liposomes, the magnetic glass ceramic and the magnetic bone cement. In the meantime, the challenges in improving the efficiency of therapy and optimizing the heat field are also discussed.

关 键 词：磁感应热疗 铁磁热籽 磁流体 磁性脂质体 磁性微晶玻璃 磁性骨水泥 

分 类 号：R730.5[医药卫生—肿瘤]