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机构地区:[1]安徽省精神卫生防治中心物质成瘾病区,合肥230022 [2]安徽省监狱总医院精神科,合肥230021
出 处:《中华行为医学与脑科学杂志》2017年第5期431-434,共4页Chinese Journal of Behavioral Medicine and Brain Science
基 金:芜湖市科技惠民计划基金(2015zd15)
摘 要:目的探讨男性酒依赖患者工作记忆特点。方法将50例男性酒依赖患者及与其人口学资料相匹配的50例健康对照组分别测量比较两组被试数字广度测试、连线测试、词汇流畅性测试,并同时比较两组在客体、语音及空间工作记忆的差异。结果酒依赖患者组在客体、语音、空间工作记忆错误数[分别为(3.76±2.20)个,3(2,5)个,(3.74±2.40)个]均差于健康对照组[分别为(2.94±1.60)个,2(1,3)个,2(1,4)个],差异有统计学意义[分别(t=2.133,P=0.035;Z=-2.400,P=0.016;z=-2.654,P=0.008)],密西根酒精使用问卷得分与语音工作记忆错误数呈正相关(r=0.371,P=0.008)。结论男性酒依赖患者存在工作记忆功能全面的损害。Objective To explore working memory in male patients with alcohol dependence. Methods 50 male patients with alcohol dependence ( AD group) and 50 healthy controls ( HC group) were assessed by digit span test, trail making test and verbal fluency test. The visual-object, visual-verbal, visual- space working memory tasks were used to measure the difference of working memory between the two groups. Results Compared with HC group, alcohol dependence group showed significant impairments in perform- ance of error number of visual-object, visual-verbal, visual-space working memory tasks (AD group: (3.76± 2.20) ,3(2,5), (3.74±2.40)) ; ( HC group: (2.94±1.60) ,2( 1,3) ,2( 1,4) ) ( t= 2.133, P= 0.035; Z= -2.400, P= 0.016; Z=-2.654, P= 0.008). Moreover, scores of Michigan alcoholism screening test were posi- tively correlated with the error number of verbal working memory task ( r=0.371, P=0.008). Conclusion The male patients with alcohol dependence exhibit impairments in all aspects of working memory.
分 类 号:R749.62[医药卫生—神经病学与精神病学]
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