健脾益气补血法对帕金森病胃肠功能障碍患者生活质量的影响  

Effect of strengthening spleen and replenishing qi and enriching blood method on quality of life of Parkinson patients with gastrointestinal dysfunction

作　　者：程云帆[1] 余晓岚[1] 蒋小玲[1] 商永华[1] 王亭如[1] 

机构地区：[1]厦门大学附属福州第二医院,福建福州350007

出　　处：《中国医药科学》2017年第7期16-18,26,共4页China Medicine And Pharmacy

基　　金：福建省福州市科技计划项目(2015-S-141-15);福建省福州市卫生计生系统科技计划项目(2015-S-wp2)

摘　　要：目的研究健脾益气补血法治疗气血亏虚型帕金森病胃肠功能障碍患者生活质量的疗效。方法将选取2015年5月~2016年11月期间的67例气血亏虚型帕金森病胃肠功能障碍患者随机分为两组,对照组35例予神经内科常规治疗,治疗组32例在神经内科常规治疗基础上予健脾益气补血汤煎服治疗。以统一帕金森病评定量表第三部分(UPDRSⅢ)、帕金森病测量问卷(PDQ-39)、胃肠道症状积分及中医老年颤证诊断和疗效评定标准判定疗效。结果治疗后两组UPDRSⅢ、帕金森病测量问卷(PDQ-39)、胃肠道症状积分评分均有下降,治疗组较对照组更明显(P<0.05)。治疗组总有效率为96.8%,对照组为77.1%,两组临床总有效率差异有统计学意义(P<0.05)。结论气血亏虚型帕金森病胃肠功能障碍予健脾益气补血法治疗效果明显。Objective To study the curative effect of strengthening spleen and replenishing qi and enriching blood method on quality of life of qi-blood deficiency Parkinson patients with gastrointestinal dysfunction. Methods 67 qi-blood deficiency Parkinson patients with gastrointestinal dysfunction who were admitted to our hospital from May 2015 to November 2016 were randomly divided into two groups. ResuIts 35 patients in the control group were given routine treatment in Department of Neurology. 32 patients in the observation group were treated by strengthening spleen and replenishing qi and enriching blood decoction at the basis of routine treatment in Department of Neurology. Curative effects were evaluated by the third part of unified Parkinson＇s disease rating scale （ UPDRS m ）, Parkinson＇s disease questionnaire （ PDQ-39 ）, gastrointestinal symptom score and diagnostic and efficacy evaluating standard of Chinese medical elderly tremor syndrome. Scores of UPDRS m , Parkinson＇s disease questionnaire （ PDQ-39 ） and gastrointestinal symptom were all decreased. And those of the treatment group were more significant than those of the control group （ P 〈 0.05 ）. Total effective rates of the treatment group and the control group were respectively 96.8% and 77.1% and the difference between two groups was statistically significant （P 〈 0.05 ）. Conclusion Strengthening spleen and replenishing qi and enriching blood method in treatment of qi-blood deficiency Parkinson patients with gastrointestinal dysfunction has significant curative effect.

关 键 词：帕金森病 胃肠功能障碍 生活质量 气血亏虚型 健脾益气补血法 

分 类 号：R742.5[医药卫生—神经病学与精神病学]