急性缺血性脑卒中患者脑微出血的相关危险因素分析  

Relative risk factors for cerebral microbleeds in patients with acute ischemic stroke

作　　者：陆云南[1] 马涛[1] 华烨[1] 

机构地区：[1]南京医科大学附属无锡第二人民医院神经内科,无锡214002

出　　处：《中国实用神经疾病杂志》2017年第11期11-14,共4页Chinese Journal of Practical Nervous Diseases

基　　金：无锡市科技发展基金(CSE1N1308)

摘　　要：目的探讨急性缺血性脑血管病患者脑微出血(CMB)发生的危险因素。方法收集急性脑梗死患者102例,根据有无CMB分为CMB组(45例)和无CMB组(57例),比较2组一般资料、生化指标,并采用多因素逐步Logistic回归模型分析CMB发生的独立危险因素。结果 2组年龄、既往脑卒中史、抗血小板药物使用史、同型半胱氨酸、胆固醇以及低密度脂蛋白胆固醇比较差异有统计学意义(P<0.1);进一步行Logistic回归分析显示,年龄、既往脑卒中史、低密度脂蛋白胆固醇(OR分别为1.066、2.861、0.106,P均<0.05)是急性脑梗死患者脑微出血发生的独立危险因素。结论 CMB的发生与年龄、卒中史、血清低密度脂蛋白胆固醇相关。Objective To investigate relative risk factors for cerebral microbleeds （CMB） in patients with acute ischemic stroke.Methods Totally 102 patients with acute cerebral infarction were divided into two groups according to the presence of CMB,and the difference of clinical data and biochemical indicators between the two groups were compared.The independent risk factors for CMB were analyzed by the Logistic multivariable regression.Results The age,history of stroke,antiplatelet therapy,plasmahomocysteine,total cholesterol,low-density lipoprotein cholesterol （LDLC） of two groups were significantly different （P〈0.1）.Logistic regression analysis showed that age,history of stroke,and LDLC were the independent risk factors for presence of CMB （OR=1.066,2.861,0.106,respectively,P〈0.05）.Conclusion CMB has relationships with age,history of stroke,and LDLC.

关 键 词：缺血性脑卒中 脑微出血 危险因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]