放射性肺损伤预测因子研究进展  

Research Progress on Prediction of Radiation-induced Lung Injury

作　　者：李芳娟[1] 王谨[2] 陈明[2] LI Fang-juan WANG Jin CHEN Ming(Shanghai Pulmonary Hospital, Tongji University School of Medicine ,Shanghai 200433, China Zhejiang Cancer Hospital,Zhejiang Key Laboratory of Radiation Oncology, Hangzhou 310022, China)

机构地区：[1]同济大学附属上海市肺科医院,上海200433 [2]浙江省肿瘤医院,浙江杭州310022

出　　处：《肿瘤学杂志》2017年第5期359-365,共7页Journal of Chinese Oncology

摘　　要：放射性肺损伤是胸部肿瘤放疗中的常见并发症,是制约放疗剂量增加及影响放疗效果的重要因素。目前严重RILI尚无有效治疗方法,早期预测RILI的发生对于疾病的治疗和预后具有重要意义。全文主要探讨生物因子、基因多态性、治疗因素、患者因素、肿瘤因素、功能影像参数等在预测RILI方面的价值。Radiation-induced lung injury（RILI） is a common complication in radiotherapy of thoracic tumors.It is an important factor that restricts the increase of radiotherapy dose and the effect of radiotherapy.At present,there is no effective treatment for severe RILI,and early prediction of RILI is very important for the treatment and prognosis of the disease.In this paper,we discuss the value of predictors from biological factors,gene polymorphism,factors related to therapy,patients,tumor and functional imaging parameters.

关 键 词：肺肿瘤 放射治疗 放射性肺损伤 放射性肺炎 

分 类 号：R734.2[医药卫生—肿瘤]