福康片联合帕罗西汀治疗甲基苯丙胺依赖患者回顾性分析  

Retrospective analysis of Fukang tablet combined with paroxetine in the treatment of subacute methamphetamine-dependent patients

作　　者：张薇 徐浩博 ZHANG Wei XU Hao-bo(The 109 hospital of Shanxi, Taiyuan city 030006)

机构地区：[1]山西省109医院,太原市030006

出　　处：《中国药物滥用防治杂志》2017年第3期146-149,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:回顾分析2014年9月到2015年9月分别用福康片加帕罗西丁和帕罗西丁在山西省109医院治疗的甲基苯丙胺患者40例,并对上述患者回访一年以上,分析复吸率,复吸原因。方法:甲基苯丙胺依赖患者40例随机分为西药组与中西药组,西药组口服帕罗西丁20mg/日治疗,中西药组在接受帕罗西丁20mg/日的基础上加用福康片第1周每天3片,每天早1片晚2片口服;第2周,每天早晚各1片口服;第3-12周以后,每晚1片口服进行治疗,观察两组患者的复吸率,并对复吸原因进行分析。结果:中西药组复吸率明显降低,差异有统计学意义(P<0.05)。通过自制复吸原因调查表调查结果显示,中西药组患者因焦虑抑郁、心里渴求等心理因素复吸患者明显少于西药组,差异有统计学意义(P<0.05)。结论:抗抑郁药物联合使用福康片能有效降低甲基苯丙胺依赖患者复吸率,且未发现明显副作用,值得临床推广。Objective： 40 patients with the methamphetamine in our hospital From September 2014 to September 2015 who were retrospectively analyzed with Fukang tablet addition of Paroxetine and Paroxetine. We followed up for one year, Analyzing the causes of relapse and relapse rate. Methods： Selection in September 2014 to September 2015 in Shanxi Province 109 hospital treatment of 40 patients with methamphetamine dependence as the research object, Were randomly divided into western medicine group with Chinese and western medicine group, The western medicine group oral Paroxetine 20 mg/day, The western medicine group with Chinese in Paroxetine 20 mg/day addition of Fukang tablet on the basis of treatment, observation of two groups of patients relapse rate, and analyzes reasons for relapse. Results： The relapse rate of The western medicine group with Chinese decreased significantly, the difference was statistically significant （P 〈 0.05）. Through the self-made questionnaire survey, relapse reasons because of Chinese and western medicine group patients psychological factors such as anxiety, depression, heart longing relapsed patients less than western medicine group obviously, the difference was statistically significant （P 〈 0.05） . Conclusion： Antidepressants combined with Fu Kang tablets can effectively reduce the MA resuscitation rate, and no significant side effects, is worthy of clinical promotion.

关 键 词：甲基苯丙胺依赖 福康片 复吸率 

分 类 号：R749.64[医药卫生—神经病学与精神病学]