多花山竹子茎叶中1个新的缩酚酸环醚化合物  

A new depsidone from stems-leaves of Garcinia multiflora

作　　者：崔笛[1] 吉炳琨 黄文忠[2] 王闪闪[1] 李银科[3] 李干鹏[1] 何永辉[1] 蒋孟圆[1] 江志勇[1] 梅双喜 杨志 高雪梅[1] 

机构地区：[1]云南民族大学民族医药学院民族药资源化学国家民委教育部重点实验室,云南昆明650500 [2]昆明学院化学科学与技术系,云南昆明650500 [3]玉溪师范学院资源环境学院,云南玉溪653100 [4]云南白药集团创新研发中心,云南昆明650500

出　　处：《中草药》2017年第9期1709-1712,共4页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(21562046;21002085;21362044);云南省科技计划项目(2016FB022);云南民族大学研究生创新基金科研项目(2016YJCXS12)

摘　　要：目的研究多花山竹子Garcinia multiflora茎叶的化学成分。方法运用硅胶、HPLC等多种色谱技术进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果从多花山竹子茎叶中分离鉴定了1个缩酚酸环醚类化合物,命名为多花山竹子缩酚酸环醚A(1);以及4个酮类化合物,分别鉴定为异巴西红厚壳素(2)、巴西红厚壳素(3)、异爪哇柘酮B(4)、2-二甲基烯丙基-1,3,5-三羟基酮(5)。结论化合物1为新化合物。化合物2~4为已知化合物,化合物2、5为首次从该植物中分离得到。Objective To study the chemical constituents in stems-leaves of Garcinia multiflora. Methods The chemical constituents from stems-leaves of G. multiflora were isolated by silica gel and HPLC methods. Their structures were elucidated by spectroscopic methods and physicochemical properties. Results One new depsidone isolated from stems-leaves of G. multiflora was named as multidepsidone A（1）, and four xanthones isolated from stems-leaves of G. multiflora were identified as isojacareubin（2）, jacareubin（3）, isocudraniaxanthone B（4）, and 2-dimethylallyl-1,3,5-trihydroxyxanthone（5）. Conclusion Compound 1 is a new compound. compounds 2—4 are known compounds, and compounds 2 and 5 are obtained from this plant for the first time.

关 键 词：多花山竹子 缩酚酸环醚类化合物 多花山竹子缩酚酸环醚A 异巴西红厚壳素 2-二甲基烯丙基-1 3 5-三羟基酮 

分 类 号：R284.1[医药卫生—中药学]