晚期胃癌分子靶向治疗进展  

Progression in molecular-targeted therapies for gastric cancer

作　　者：罗会芹[1] 何义富[2] 

机构地区：[1]安徽省立医院西区安徽省肿瘤医院肿瘤内一科,合肥230001 [2]安徽省立医院肿瘤化疗科,230001

出　　处：《临床肿瘤学杂志》2017年第5期455-460,共6页Chinese Clinical Oncology

基　　金：安徽省自然科学基金资助项目(1408085MH179)

摘　　要：我国胃癌发病率高,由于早期临床症状不典型以及早期胃癌的筛查重视度不够,多数患者确诊时已处于疾病晚期。传统化疗一直是晚期胃癌主要的治疗选择,然而单纯化疗的疗效仍十分有限且已达到瓶颈。随着肿瘤分子生物学的研究深入,分子靶向治疗为晚期胃癌的治疗带来了新的曙光和希望。本文拟就近几年胃癌靶向治疗的新进展作一综述,分析药物的有效性和安全性,为临床治疗提供一些参考。Incidence of gastric cancer in China is almost half of the morbidity in the world.Because the early clinical symptoms are not typical and early gastric cancer screening is not enough in China, the majority of patients diagnosed with advanced gastric cancer.Traditional chemotherapy was the mainly treatment options for advanced gastric cancer, but the curative effect of chemotherapy was still limited and reached the bottleneck.With the research development of tumor molecular biology, molecular-targeted therapy for the treatment of advanced gastric cancer has brought a new dawn and hope.This thesis summarizes the new progression in targeted therapy of gastric carcinoma in recent years, analyzes the drug efficacy and safety, and provides some references for clinical treatment.

关 键 词：胃癌 靶向治疗 进展 

分 类 号：R735.2[医药卫生—肿瘤]