机构地区:[1]首都医科大学附属北京朝阳医院神经内科,北京市100020 [2]同济大学医学院病理学与病理生理学系,上海市200092 [3]复旦大学生命科学学院,上海市200433
出 处:《中国全科医学》2017年第18期2193-2196,共4页Chinese General Practice
基 金:国家自然科学基金资助项目(81301015;81571372;81670465);北京市自然科学基金资助项目(7141001)
摘 要:背景老年人的认知功能和躯体运动功能均会有不同程度的减退,老年人认知功能与简单的运动功能的相关性鲜见报道。目的探讨老年认知功能障碍(CI)与运动功能的相关性。方法 2014-11-13至2014-12-21从如皋市江安镇招募了1 788例年龄为70~84岁的老年人。根据改良长谷川痴呆量表(HDS-R)评分分为正常组(≥31.0分)、边缘状态组(22.0~30.5分)、可疑痴呆组(10.5~21.5分)、痴呆组(≤10.0分),采用起立-行走计时测试检测老年人运动功能,记录测试时间、步态稳定性及摔倒危险性评分。结果共1 655例老年人完成HDS-R及起立-行走计时测试,其中正常组109例、边缘状态组674例、可疑痴呆组833例、痴呆组39例。正常组测试时间短于边缘状态组、可疑痴呆组、痴呆组,步态稳定率高于可疑痴呆组、痴呆组,摔倒危险性评分低于可疑痴呆组、痴呆组(P<0.05);边缘状态组测试时间短于可疑痴呆组、痴呆组,步态稳定率高于可疑痴呆组、痴呆组,摔倒危险性评分低于可疑痴呆组、痴呆组(P<0.05);可疑痴呆组测试时间短于痴呆组,摔倒危险性评分低于痴呆组(P<0.05)。HDS-R评分与起立-行走计时测试的测试时间、步态稳定率和摔倒危险性评分呈负相关(相关系数分别为-0.243、-0.120和-0.163,P<0.001)。结论老年人认知功能和躯体运动功能减退,随着步态不稳定以及摔倒危险性的增加,CI的风险明显增加。Background The cognitive and motor functions in the elderly decrease in different degree,but the relationship between them has been seldom reported.Objective To investigate the correlation between cognitive impairment(CI) and motor function in the elderly.Methods The participants were 1 788 70-84-year-old elderly people recruited from Jiang′an Town,Rugao City of China between November 13th and December 21st,2014.Based on the scores of Hasegawa′s Dementia Scale-Revised(HDS-R),they were divided into normal group(≥31.0),conditions between the normal and suspected dementia group(22.0-30.5),suspected dementia group(10.5-21.5) and dementia group(≤10.0).The body movement function of the elderly population was measured by timed up and go(TUG) test.The time needed to complete the TUG test,status of gait stability and the risk of falling were recorded.Results A total of 1 655 participants completed the assessment of cognitive function with the HDS-R,and TUG test,including 109 in the normal group,674 in conditions between the normal and suspected dementia group,833 in suspected dementia group and 39 in dementia group.Among the four groups,participants in the normal group used the least time to complete the TUG test,and they had the highest gait stability rate,and lowest risk of falling(P〈0.05).Compared with the suspected dementia group and dementia group,conditions between the normal and suspected dementia group used less time to finish the TUG test,owned higher gait stability rate,and lower risk of falling(P〈0.05).Suspected dementia group used less time to complete the TUG test,and owned lower risk of falling than the dementia group(P〈0.05).The score of HDS-R presented a negative correlation with the time needed to complete the TUG test,with a correlation coefficient of-0.243,P〈0.001.The score of HDS-R was negatively correlated with the status of gait stability with a correlation coefficient of-0.120,P〈0.001.The score of HDS-R was negatively associated with the risk
分 类 号:R741[医药卫生—神经病学与精神病学]
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