侵袭性纤维瘤病的非手术治疗  

Non-surgical Treatment of Aggressive Fibromatosis

作　　者：罗恒(综述) 张石川[1,2] 樊晋川(审校)[1,2] 

机构地区：[1]西南医科大学附属医院肿瘤科,四川泸州646000 [2]四川省肿瘤医院·研究所,四川省癌症防治中心·电子科技大学医学院,成都610041

出　　处：《肿瘤预防与治疗》2017年第3期203-207,共5页Journal of Cancer Control And Treatment

摘　　要：侵袭性纤维瘤病(aggressive fibromatosis,AF)是介于良恶性之间的交界性肿瘤,以局部浸润和高复发率为特点。AF的治疗既往以手术切除为主,但单纯手术复发率较高,盲目的手术往往造成患者机能或外形的损伤。近年来,包括内分泌治疗、手术、放疗、化疗、非甾体抗炎药物治疗、靶向药物、干扰素等多种治疗手段得到尝试,并取得一定疗效。此外,鉴于AF的惰性特征,观察等待也是多个行业指南推荐的一线方案。在AF的治疗决策上,必须综合考虑患者需求,注重机体功能和外形的保全,将非手术手段放到与手术同等地位加以考虑。In recent years, multiple modalities including endocrine therapy, surgery combined with radiotherapy, chemotherapy, non-steroidal anti-inflammatory drug treatment,targeted drugs, and interferon treatment have been tried and achieved comparable success. In addition, based on the indolent nature of AF,observation is also recommended as first-line treatment by severalguidelines.For the treatment decision making of AF,the patients’expectation must be considered,function preservation and cosmetic requirement need to be emphasized,and non-surgical treatment should be considered as important as surgery.

关 键 词：侵袭性纤维瘤病 非手术治疗 药物治疗 放疗 

分 类 号：R730.262[医药卫生—肿瘤] R730.5[医药卫生—临床医学]