子宫肌瘤剔除术对不孕女性妊娠的影响及影响术后妊娠的相关因素分析  

Analysis of the influence of uterine myomectomy on the pregnancy of infertile women and the related factors

作　　者：刘素芳[1] 姜泽允[1] 郑凤俊 马刚 冀雪霞[1] 

机构地区：[1]哈励逊国际和平医院,河北衡水053000

出　　处：《重庆医学》2017年第A01期8-11,共4页Chongqing medicine

基　　金：国家杰出青年科学基金资助项目（H2707）.

摘　　要：目的研究分析合并子宫肌瘤的不孕妇女行子宫肌瘤剔除术后妊娠情况及影响术后妊娠的原因。方法随机选取该院2012年5月至2015年6月行子宫肌瘤剔除术患者150例，并回顾性分析150例患者的一般资料、肌瘤特征及术后随访情况。结果患者术后总妊娠率为52．0％（78／150），胎儿存活率为69．2％（54／78）；术后妊娠的危险因子为年龄[风险比（RR）-0．99，95％可信区间（95％CI）：0．98～1．31，P=0．05]，与不孕种类及时间、孕产史，以及肌瘤数量、大小、质地、种类等均无关。结论不孕合并子宫肌瘤妇女行子宫肌瘤剔除术后可提高患者的妊娠率和胎儿存活率，年龄是术后妊娠的危险因子，与妊娠率呈负相关，因此可根据患者实际年龄决定是否行子宫肌瘤剔除术。Objective To analyze the influence of uterine myomectomy on the pregnancy of infertile women and the related fac- tors. Methods 150 patients implemented with this operation in our hospital during May 2012 and 2015 June were selected by the method of random, and we analyzed all subjects of general information, characteristics and postoperative follow--up of myoma retro- spectively. Results According to the results of follow-up of 1-2 years,the total postoperative pregnancy rate was 52% （78/150）, and the fetal survival rate was 69.2%（54/78） ;The Cox regression analysis showed that the age was the risk factors of postopera- tive pregnancy （RR = O. 99,95 % CI ： 0.98- 1.31, P〈0.05）, and it was related to the type of infertility, infertility, pregnancy history and the myoma number,size,texture, type,etc. Conclusion Infertile women with uterine fibroids after myomectomy could improve the pregnancy rate and fetal survival rate, age was a risk factor for postoperative pregnancy and pregnancy, which was negatively correlated with pregnancy rate. So the patients could decide whether to take myomectomy or not according to the actual age.

关 键 词：子宫肌瘤剔除术 不孕 妊娠 手术与有关 

分 类 号：R737.33[医药卫生—肿瘤]